Hydrogel-encapsulated lipid membranes.

Hydrogel-encapsulated lipid membranes. Research Abstract Details 

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Hydrogel-encapsulated lipid membranes. Abstract Text:

Tae-Joon Jeon,Noah Malmstadt,Jacob J Schmidt,

We have encapsulated free-standing planar lipid membranes in a polymer hydrogel via in situ photopolymerization. These encapsulated membranes were measured to last at least 5 days and provided a stable environment for single-molecule measurements of incorporated alpha-hemolysin channel proteins. The translocation of single-stranded DNA through alpha-hemolysin incorporated into these encapsulated membranes is slowed over 100 times relative to that of the gel-free state. These stabilized membranes, therefore, have application to the single-molecule analysis of DNA as well as broader application to biomolecular sensors, membrane protein biophysical studies, and drug discovery.

Hydrogel-encapsulated lipid membranes. Publishing Authors By Initials

TJ Jeon,N Malmstadt,JJ Schmidt,

For similar biomedical and dental materials: membranes, artificial research abstracts see: biomedical and dental materials: membranes, artificial research

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Hydrogel-encapsulated lipid membranes. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the American Chemical Society

VOLUME: 128

Page Numbers: 42-3

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 11

MONTH: Jan

YEAR: 2006

Hydrogel-encapsulated lipid membranes. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Hydrogel-encapsulated lipid membranes. Keywords Mesh Terms:

KEYWORDS: Membranes, Artificial

MESH TERMS: metabolism

Chemical & Substance for Abstract: Hydrogel-encapsulated lipid membranes. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Hydrogel-encapsulated lipid membranes.

AFFILIATION: Department of Bioengineering, University of California-Los Angeles, Los Angeles, CA 90095, USA.

Country: United States

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MEDLINETA: J Am Chem Soc

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