Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz.

Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Research Abstract Details 

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Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Abstract Text:

Hyaluronic acid, a connective tissue component, in bronchoalveolar lavage fluid (BAL) is correlated with decreased lung volumes in sarcoidosis. To investigate whether hyaluronic acid could be a marker of fibrosis in another interstitial lung disease, silicosis, the level of the substance in BAL fluid from rats exposed to crystalline silica (n = 3), amorphous silica (n = 3), and in one sham injected rat was measured. There was an increase in the total number of alveolar cells recovered in the rats exposed to crystalline silica and also a pronounced increase in the proportions of neutrophils and lymphocytes. In addition, the concentration of hyaluronic acid was high in this group of rats, and electron microscopic investigation of the lungs showed fibrosis. Thus hyaluronate in BAL fluid in rats exposed to crystalline silica seems to be a possible marker of fibrotic changes.

Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Publishing Authors By Initials

For similar respiratory tract diseases: lung diseases: lung diseases, interstitial: pneumoconiosis: silicosis research abstracts see: respiratory tract diseases: lung diseases: lung diseases, interstitial: pneumoconiosis: silicosis research

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Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: British journal of industrial medicine

VOLUME: 44

Page Numbers: 443-5

Journal Abbreviation: Br J Ind Med

ISSN: 0007-1072

DAY: 28

MONTH: Jul

YEAR: 1987

Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Information

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LANGUAGE: eng

NlmUniqueID: 370637

Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Keywords Mesh Terms:

KEYWORDS: Silicosis

MESH TERMS: pathology

Chemical & Substance for Abstract: Hyaluronic acid in bronchoalveolar lavage in rats exposed to quartz. Information

Substance Name: Hyaluronic Acid

Registry Number: 9004-61-9

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Country: ENGLAND

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MEDLINETA: Br J Ind Med

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