Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues.

Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Research Abstract Details 

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Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Abstract Text:

K Oishi,K Sakamoto,T Okada,T Nagase,N Ishida,

Northern blot analysis revealed the circadian expression of rat period homologue (rPer2) mRNA in peripheral mononuclear leukocytes that have no neuronal connections. The mRNA expression in the suprachiasmatic nucleus (SCN), peripheral mononuclear leukocytes, and other peripheral tissues exhibited prominent, synchronous circadian oscillation with peaks at early night. As we have previously shown the peripheral circadian expression of rPer2 mRNA is abolished in SCN-lesioned rats [Sakamoto, K., Nagase, T. Fukui, H., Horikawa, K., Okada, T., Tanaka, H., Sato, K., Miyake, Y., Ohara, O., Kako, K. and Ishida, N., J. Biol. Chem., 273 (1998) 27039-27042], our findings suggest that some humoral signals, driven by the SCN, mediate the circadian expression of mammalian per homologues in peripheral tissues.

Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Publishing Authors By Initials

K Oishi,K Sakamoto,T Okada,T Nagase,N Ishida,

For similar proteins: transcription factors research abstracts see: proteins: transcription factors research

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Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neuroscience letters

VOLUME: 256

Page Numbers: 117-9

Journal Abbreviation: Neurosci. Lett.

ISSN: 0304-3940

DAY: 6

MONTH: Nov

YEAR: 1998

Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Information

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LANGUAGE: eng

NlmUniqueID: 7600130

Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: metabolism

Chemical & Substance for Abstract: Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues. Information

Substance Name: Transcription Factors

Registry Number: 0

Grant and Affiliation Information for Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues.

AFFILIATION: Ishida Group of Clock Gene, National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Tsukuba, Ibaraki, Japan.

Country: IRELAND

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MEDLINETA: Neurosci Lett

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