Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation.

Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation. Research Abstract Details 

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Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation. Abstract Text:

This report describes a patient who developed human T-cell leukemia virus type I-associated myelopathy (HAM) following a living-donor liver transplantation (LDLT) for liver cirrhosis due to hepatitis C virus (HCV) infection. Both the recipient and the living donor (his sister) were human T-cell leukemia virus type I (HTLV-I) carriers. Since the LDLT, he had been treated with immunosuppressive drugs such as tacrolimus and steroids as well as interferon-alpha to prevent rejection and a recurrence of the HCV infection, respectively. Even though the HTLV-I proviral load had decreased upon interferon treatment, he developed a slowly progressive gait disturbance with urinary disturbance 2 years after the LDLT and was diagnosed with HAM. This appears to be the first report of HAM development in an HLTV-I-infected LDLT recipient. Liver Transpl 14:647-650, 2008. (c) 2008 AASLD.

Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation. Publishing Authors By Initials

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Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Liver transplantation : official publication of th

VOLUME: 14

Page Numbers: 647-50

Journal Abbreviation: Liver Transpl.

ISSN: 1527-6473

DAY: 30

MONTH: May

YEAR: 2008

Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation.

AFFILIATION: Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Country: United States

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MEDLINETA: Liver Transpl

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