Human scleral elastic system: an immunoelectron microscopic study.

Human scleral elastic system: an immunoelectron microscopic study. Research Abstract Details 

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Human scleral elastic system: an immunoelectron microscopic study. Abstract Text:

An immunocytochemical study was conducted on elastic components in the sclera of seven aged human eyes. By conventional electron microscopy, elastic tissue consists of three distinct fibre types--elastic fibres, elaunin fibres, and oxytalan fibres. The distribution of six components associated with the elastic system (elastin, amyloid P component, laminin, fibronectin, gp 115, and vitronectin) were studied by immunogold transmission electron microscopy. The codistribution of amyloid P component and laminin was further studied by double immunolabelling. Both elastic and elaunin fibres contained elastin. The microfibrillar sheaths of elastic fibres labelled for amyloid P component, those of elaunin fibres for amyloid P and laminin, and those of oxytalan fibres for laminin only. No labelling was observed for fibronectin, gp 115, and vitronectin. In terms of the proteins investigated, the biochemical profile of the three fibre types was not completely identical and was manifest as different affinities in the binding of serum amyloid P component and an association with laminin.

Human scleral elastic system: an immunoelectron microscopic study. Publishing Authors By Initials

For similar proteins: blood proteins: vitronectin research abstracts see: proteins: blood proteins: vitronectin research

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Human scleral elastic system: an immunoelectron microscopic study. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The British journal of ophthalmology

VOLUME: 79

Page Numbers: 57-64

Journal Abbreviation: Br J Ophthalmol

ISSN: 0007-1161

DAY: 28

MONTH: Jan

YEAR: 1995

Human scleral elastic system: an immunoelectron microscopic study. Information

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LANGUAGE: eng

NlmUniqueID: 421041

Human scleral elastic system: an immunoelectron microscopic study. Keywords Mesh Terms:

KEYWORDS: Vitronectin

MESH TERMS: analysis

Chemical & Substance for Abstract: Human scleral elastic system: an immunoelectron microscopic study. Information

Substance Name: Elastin

Registry Number: 9007-58-3

Grant and Affiliation Information for Human scleral elastic system: an immunoelectron microscopic study.

AFFILIATION: Tennent Institute of Ophthalmology, University of Glasgow Western Infirmary.

Country: ENGLAND

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MEDLINETA: Br J Ophthalmol

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