Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx.

Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Research Abstract Details 

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Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Abstract Text:

M Poljak,N Gale,V Kambic,

This study investigated the prevalence of human papillomavirus (HPV) infection in various laryngeal epithelial hyperplastic lesions using the Kambic classification from simple hyperplasia to invasive squamous cell carcinoma. For detection of HPV infection polymerase chain reaction (PCR) with 3 different HPV consensus primer sets and in situ hybridization were used. The presence of the HPV DNA was detected in only 2 of the 88 specimens tested: HPV type 6 was detected in 1 case of simple hyperplasia and HPV type 16 in 1 case of invasive squamous cell carcinoma. In conclusion, our study suggests that most laryngeal epithelial hyperplastic lesions are not associated with HPV infection and that other pathogenic mechanisms are more important in the etiology of these lesions.

Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Publishing Authors By Initials

M Poljak,N Gale,V Kambic,

For similar virus diseases: tumor virus infections research abstracts see: virus diseases: tumor virus infections research

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Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 527

Page Numbers: 66-9

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ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1997

Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Information

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LANGUAGE: eng

NlmUniqueID: 370355

Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx. Keywords Mesh Terms:

KEYWORDS: Tumor Virus Infections

MESH TERMS: epidemiology

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Grant and Affiliation Information for Human papillomaviruses: a study of their prevalence in the epithelial hyperplastic lesions of the larynx.

AFFILIATION: Institute of Microbiology and Immunology, Medical Faculty of Ljubljana, Slovenia. poljak@ibmi.mf.uni-lj.si

Country: NORWAY

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MEDLINETA: Acta Otolaryngol Suppl

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