Human metapneumovirus in turkey poults.

Human metapneumovirus in turkey poults. Research Abstract Details 

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Human metapneumovirus in turkey poults. Abstract Text:

Binu T Velayudhan,Kakambi V Nagaraja,Anil J Thachil,Daniel P Shaw,Gregory C Gray,David A Halvorson,

This study was conducted to reexamine the hypothesis that human metapneumovirus (hMPV) will not infect turkeys. Six groups of 2-week-old turkeys (20 per group) were inoculated oculonasally with 1 of the following: noninfected cell suspension; hMPV genotype A1, A2, B1, or B2; or avian metapneumovirus (aMPV) subtype C. Poults inoculated with hMPV showed nasal discharge days 4-9 postexposure. Specific viral RNA and antigen were detected by reverse-transcription PCR and immunohistochemical evaluation, respectively, in nasal turbinates of birds exposed to hMPV. Nasal turbinates of hMPV-infected turkeys showed inflammatory changes and mucus accumulation. Each of the 4 hMPV genotypes caused a transient infection in turkeys as evidenced by clinical signs, detection of hMPV in turbinates, and histopathologic examination. Detailed investigation of cross-species pathogenicity of hMPV and aMPV and its importance for human and animal health is needed.

Human metapneumovirus in turkey poults. Publishing Authors By Initials

BT Velayudhan,KV Nagaraja,AJ Thachil,DP Shaw,GC Gray,DA Halvorson,

For similar animals: chordata: vertebrates: birds: galliformes: turkeys research abstracts see: animals: chordata: vertebrates: birds: galliformes: turkeys research

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MEDLINE DATE:

Human metapneumovirus in turkey poults. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Emerging infectious diseases

VOLUME: 12

Page Numbers: 1853-9

Journal Abbreviation: Emerging Infect. Dis.

ISSN: 1080-6040

DAY: 3

MONTH: Dec

YEAR: 2006

Human metapneumovirus in turkey poults. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9508155

Human metapneumovirus in turkey poults. Keywords Mesh Terms:

KEYWORDS: Turkeys

MESH TERMS: virology

Chemical & Substance for Abstract: Human metapneumovirus in turkey poults. Information

Substance Name: RNA, Viral

Registry Number: 0

Grant and Affiliation Information for Human metapneumovirus in turkey poults.

AFFILIATION: University of Minnesota, Saint Paul, MN 55108, USA.

Country: United States

AGENCY: United States NIAID

GRANT: R03 AI054570-01A1

ACRONYM: AI

MEDLINETA: Emerg Infect Dis

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