Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism.

Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Research Abstract Details 

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Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Abstract Text:

We found a novel A-->G change at nucleotide 1968 within the 3'-untranslated region of the HNF1B gene encoding the hepatocyte nuclear factor-1 beta. The HNF1B 1968A/G polymorphism could be detected by digestion with endonuclease MspI. The frequency of the HNF1B 1968G allele was 0.060 in Caucasians and 0.129 in Canadian Oji-Cree. Because of the importance of the HNF1B gene product in the regulation of transcription of several hepatic proteins, this polymorphism may be useful in the study of associations with metabolic phenotypes such as diabetes.

Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Publishing Authors By Initials

For similar proteins: transcription factors research abstracts see: proteins: transcription factors research

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Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of human genetics

VOLUME: 45

Page Numbers: 98-9

Journal Abbreviation: J. Hum. Genet.

ISSN: 1434-5161

DAY: 14

MONTH: 05

YEAR: 2000

Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Information

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LANGUAGE: eng

NlmUniqueID: 9808008

Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: genetics

Chemical & Substance for Abstract: Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism. Information

Substance Name: Hepatocyte Nuclear Factor 1-beta

Registry Number: 138674-15-4

Grant and Affiliation Information for Human hepatocyte nuclear factor-1 beta (HNF1B) 1968A/G polymorphism.

AFFILIATION: Blackburn Cardiovascular Genetics Laboratory, John P. Robarts Research Institute, London, Ontario, Canada.

Country: JAPAN

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MEDLINETA: J Hum Genet

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