Human fetal iridocorneal angle: a light and scanning electron microscopic study.

Human fetal iridocorneal angle: a light and scanning electron microscopic study. Research Abstract Details 

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Human fetal iridocorneal angle: a light and scanning electron microscopic study. Abstract Text:

The iridocorneal angle and inner layers of the trabecular meshwork in human fetal eyes were studied by scanning electron microscopy. Tissue from 32 eyes of 17 fetuses with a gestational age from 12 to 22 weeks were investigated in order to determine the morphological changes in the cellular lining of the anterior chamber angle recess during development. The findings indicate that, although hexagonal corneal endothelial profiles extend almost to the angle apex in a few of the younger eyes examined (12-14 weeks), the lining is always perforated by a few discrete intercellular gaps (2-6 microns diameter). As development progresses it becomes clearer that the maturing meshwork is lined by uveal trabecular endothelial cells which are morphologically distinguishable from corneal endothelium. The frequency and size of the gaps between the inner uveal trabecular endothelial cells increase and are well developed by 18-20 weeks, clearly providing a route of communication between the fetal anterior chamber and the developing intercellular spaces in the primitive trabecular tissue. The implications of these observations on the 'Barkan's membrane' theory of congenital glaucoma are discussed.

Human fetal iridocorneal angle: a light and scanning electron microscopic study. Publishing Authors By Initials

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: microscopy: microscopy, electron: microscopy, electron, scanning research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: microscopy: microscopy, electron: microscopy, electron, scanning research

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Human fetal iridocorneal angle: a light and scanning electron microscopic study. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The British journal of ophthalmology

VOLUME: 73

Page Numbers: 871-9

Journal Abbreviation: Br J Ophthalmol

ISSN: 0007-1161

DAY: 28

MONTH: Nov

YEAR: 1989

Human fetal iridocorneal angle: a light and scanning electron microscopic study. Information

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LANGUAGE: eng

NlmUniqueID: 421041

Human fetal iridocorneal angle: a light and scanning electron microscopic study. Keywords Mesh Terms:

KEYWORDS: Microscopy, Electron, Scanning

MESH TERMS: ultrastructure

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Grant and Affiliation Information for Human fetal iridocorneal angle: a light and scanning electron microscopic study.

AFFILIATION: Department of Anatomy and Human Biology, University of Western Australia, Nedlands, Perth.

Country: ENGLAND

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MEDLINETA: Br J Ophthalmol

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