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Human cerebral cortex: a system for the integration of volume- and surface-based representations.

Human cerebral cortex: a system for the integration of volume- and surface-based representations. Research Abstract Details 

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  • Human cerebral cortex: a system for the integration of volume- and surface-based representations. Abstract Text:

    nikos makrisNikos Makris,jonathan kaiserJonathan Kaiser,christian haselgroveChristian Haselgrove,larry j seidmanLarry J Seidman,joseph biedermanJoseph Biederman,denise borielDenise Boriel,eve m valeraEve M Valera,george m papadimitriouGeorge M Papadimitriou,bruce fischlBruce Fischl,verne s cavinessVerne S Caviness,david n kennedyDavid N Kennedy,

    We describe an MRI-based system for topological analysis followed by measurements of topographic features for the human cerebral cortex that takes as its starting point volumetric segmentation data. This permits interoperation between volume-based and surface-based topographic analysis and extends the functionality of many existing segmentation schemes. We demonstrate the utility of these operations in individual as well as to group analysis. The methodology integrates analyses of cortical segmentation data generated by manual and semi-automated volumetric morphometry routines (such as the program cardviews) with the procedures of the FreeSurfer program to generate a cortical ribbon of the cerebrum and perform cortical topographic measurements (including thickness, surface area and curvature) in individual subjects as well as in subject populations. This system allows the computation of topographical cortical measurements for segmentation data generated from manual and semi-automated volumetric sources other than FreeSurfer. These measurements can be regionally specific and integrated with systems of cortical parcellation that subdivides the neocortex into gyral-based parcellation units (PUs). This system of topographical analysis of the cerebral cortex is consistent with current views of cortical development and neural systems organization of the human and non-human primate brain.

    Human cerebral cortex: a system for the integration of volume- and surface-based representations. Publishing Authors By Initials

    n makrisN Makris,j kaiserJ Kaiser,c haselgroveC Haselgrove,lj seidmanLJ Seidman,j biedermanJ Biederman,d borielD Boriel,em valeraEM Valera,gm papadimitriouGM Papadimitriou,b fischlB Fischl,vs cavinessVS Caviness,dn kennedyDN Kennedy,

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    Human cerebral cortex: a system for the integration of volume- and surface-based representations. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: NeuroImage

    VOLUME: 33

    Page Numbers: 139-53

    Journal Abbreviation:

    ISSN: 1053-8119

    DAY: 22

    MONTH: 08

    YEAR: 2006

    Human cerebral cortex: a system for the integration of volume- and surface-based representations. Information

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    LANGUAGE: eng

    NlmUniqueID: 9215515

    Human cerebral cortex: a system for the integration of volume- and surface-based representations. Keywords Mesh Terms:

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    Grant and Affiliation Information for Human cerebral cortex: a system for the integration of volume- and surface-based representations.

    AFFILIATION: Center for Morphometric Analysis, MGH-East, 149 13th Street, Charlestown, MA 02129, USA. nikos@cma.mgh.harvard.edu

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Neuroimage

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