Human bone microstructure studied by collagenase etching.

Human bone microstructure studied by collagenase etching. Research Abstract Details 

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Human bone microstructure studied by collagenase etching. Abstract Text:

I G Mackie,M Green,H Clarke,D H Isaac,

Bone samples from the iliac crest of patients with no signs of bone disorder were treated with collagenase to remove the collagen component and so allow detailed observation of the mineral hydroxyapatite. Both polished and unpolished surfaces were studied in the scanning electron microscope and they showed that the mineral component of bone is composed of small rounded units about 10 nm across which are fused together to form larger spheroidal units roughly 100 nm in diameter. In the unpolished surfaces these 100 nm units are seen to aggregate to form columns approximately parallel to their neighbours and with numerous interconnections forming a continuous mineral phase. The polished sections also show the hydroxyapatite as a continuous phase of contiguous spheroids and the holes from which the collagen fibres were removed are clearly revealed. Lamellations in the surface are interpreted as resulting from adjacent layers of collagen fibres having orientations approximately perpendicular to each other.

Human bone microstructure studied by collagenase etching. Publishing Authors By Initials

IG Mackie,M Green,H Clarke,DH Isaac,

For similar inorganic chemicals: minerals research abstracts see: inorganic chemicals: minerals research

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Human bone microstructure studied by collagenase etching. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Journal of bone and joint surgery. British vol

VOLUME: 71

Page Numbers: 509-13

Journal Abbreviation:

ISSN: 0301-620X

DAY: 14

MONTH: May

YEAR: 1989

Human bone microstructure studied by collagenase etching. Information

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LANGUAGE: eng

NlmUniqueID: 375355

Human bone microstructure studied by collagenase etching. Keywords Mesh Terms:

KEYWORDS: Minerals

MESH TERMS: analysis

Chemical & Substance for Abstract: Human bone microstructure studied by collagenase etching. Information

Substance Name: Microbial Collagenase

Registry Number: EC 3.4.24.3

Grant and Affiliation Information for Human bone microstructure studied by collagenase etching.

AFFILIATION: Department of Traumatic and Orthopaedic Surgery, UWCM, Cardiff Royal Infirmary, Wales.

Country: ENGLAND

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MEDLINETA: J Bone Joint Surg Br

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