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How to build a biofilm: a fungal perspective.

How to build a biofilm: a fungal perspective. Research Abstract Details 

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  • How to build a biofilm: a fungal perspective. Abstract Text:

    jill r blankenshipJill R Blankenship,aaron p mitchellAaron P Mitchell,

    Biofilms are differentiated masses of microbes that form on surfaces and are surrounded by an extracellular matrix. Fungal biofilms, especially those of the pathogen Candida albicans, are a cause of infections associated with medical devices. Such infections are particularly serious because biofilm cells are relatively resistant to many common antifungal agents. Several in vitro models have been used to elucidate the developmental stages and processes required for C. albicans biofilm formation, and recent studies have begun to define biofilm genetic control. It is clear that cell-substrate and cell-cell interactions, hyphal differentiation and extracellular matrix production are key steps in biofilm development. Drug resistance is acquired early in biofilm formation, and appears to be governed by different mechanisms in early and late biofilms. Quorum sensing might be an important factor in dispersal of biofilm cells. The past two years have seen the emergence of several genomic strategies to uncover global events in biofilm formation and directed studies to understand more specific events, such as hyphal formation, in the biofilm setting.

    How to build a biofilm: a fungal perspective. Publishing Authors By Initials

    jr blankenshipJR Blankenship,ap mitchellAP Mitchell,

    For similar biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: signal transduction research abstracts see: biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: signal transduction research

    PUBMED ID PMID:

    MEDLINE DATE:

    How to build a biofilm: a fungal perspective. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Current opinion in microbiology

    VOLUME: 9

    Page Numbers: 588-94

    Journal Abbreviation: Curr. Opin. Microbiol.

    ISSN: 1369-5274

    DAY: 20

    MONTH: 10

    YEAR: 2006

    How to build a biofilm: a fungal perspective. Information

    Number of References: 44

    LANGUAGE: eng

    NlmUniqueID: 9815056

    How to build a biofilm: a fungal perspective. Keywords Mesh Terms:

    KEYWORDS: Signal Transduction

    MESH TERMS: physiology

    Chemical & Substance for Abstract: How to build a biofilm: a fungal perspective. Information

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    Grant and Affiliation Information for How to build a biofilm: a fungal perspective.

    AFFILIATION: Department of Microbiology, Hammer Health Sciences Center, Room 906, 701 W 168th Street, New York, NY 10032, USA.

    Country: England

    England Research PublicationEngland Research Publication

    AGENCY: United States NIAID

    GRANT: R01 AI067703

    ACRONYM: AI

    MEDLINETA: Curr Opin Microbiol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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