Menopause is defined as the permanent cessation of menses, as a result of the loss of ovarian follicular function or of surgical removal of ovaries. The mean age for occurrence of natural menopause is around 50 years. Estrogen deficiency has been associated with vasomotor symptoms, urogenital atrophy, and cognitive impairment, as well as increased risk of chronic degenerative diseases such as osteoporosis and Alzheimers disease. Estrogen therapy remains the most effective treatment for the management of vasomotor symptoms and urogenital atrophy. Progesterone or progestins should be added to estrogen treatment in women with uterus, in order to antagonize the estrogen-induced endometrial proliferation. In turn, in specific clinical conditions hormone therapy is not recommended. In the present article, the authors critically focus these clinical conditions in which hormone therapy should not be used.
[Hormone therapy in menopause: when not to use.] Publishing Authors By Initials
[Hormone therapy in menopause: when not to use.] Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Arquivos brasileiros de endocrinologia e metabolog
VOLUME: 51
Page Numbers: 1058-63
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ISSN: 0004-2730
DAY: 24
MONTH: Oct
YEAR: 2007
[Hormone therapy in menopause: when not to use.] Information
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LANGUAGE: por
NlmUniqueID: 403437
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AFFILIATION: Unidade de Endocrinologia Ginecológica, Serviço de Endocrinologia, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS.
Country: Brazil
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MEDLINETA: Arq Bras Endocrinol Metabol
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