HIV incidence among injection drug users in Baltimore, Maryland (1988-2004).

HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Research Abstract Details 

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HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Abstract Text:

Shruti H Mehta,Noya Galai,Jacquie Astemborski,David D Celentano,Steffanie A Strathdee,David Vlahov,Kenrad E Nelson,

BACKGROUND: We examined recent trends (1999-2004) in HIV incidence among a cohort of injection drug users (IDUs) followed since 1988 in Baltimore, Maryland. METHODS: One thousand eighty-three HIV-seronegative individuals with a history of injection drug use were recruited between 1988 and 1998 and returned for >or=1 semiannual follow-up visit, where they underwent HIV antibody testing and interviews eliciting risk behaviors. Person-time methods were used to calculate HIV incidence rates per 100 person-years (PYs). RESULTS: Over 14,770 PYs, 304 individuals seroconverted to HIV (2.06 per 100 PYs). Annual incidence declined from 4.57 in 1988 to 0.53 per 100 PYs in 2004. Similarly, among individuals actively injecting drugs, incidence steadily declined from 5.43 in 1988 to 0 in 2004, with the exception of 2003, when an incidence of 2.59 per 100 PYs was observed. Reported sexual risk behaviors and drug injection declined from 1988 through 2004, but among those actively injecting, reported needle sharing declined from 1988 through 1998 and then increased from 30% in 1998 to nearly 40% in 2003 through 2004. CONCLUSIONS: Long-term declines in HIV incidence among IDUs are consistent with other reports; however, in 2003, we observed an unexpected increase in seroconversion that seems to be related to needle sharing. Although additional follow-up is needed to identify trends, these data indicate the need to reinforce HIV prevention efforts and to continue surveillance of drug users' behaviors.

HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Publishing Authors By Initials

SH Mehta,N Galai,J Astemborski,DD Celentano,SA Strathdee,D Vlahov,KE Nelson,

For similar disorders of environmental origin: substance-related disorders: substance abuse, intravenous research abstracts see: disorders of environmental origin: substance-related disorders: substance abuse, intravenous research

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HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of acquired immune deficiency syndromes (1

VOLUME: 43

Page Numbers: 368-72

Journal Abbreviation: J. Acquir. Immune Defic. Syndr

ISSN: 1525-4135

DAY: 1

MONTH: Nov

YEAR: 2006

HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100892005

HIV incidence among injection drug users in Baltimore, Maryland (1988-2004). Keywords Mesh Terms:

KEYWORDS: Substance Abuse, Intravenous

MESH TERMS: complications

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Grant and Affiliation Information for HIV incidence among injection drug users in Baltimore, Maryland (1988-2004).

AFFILIATION: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21202, USA. shmehta@jhsph.edu

Country: United States

AGENCY: United States NIDA

GRANT: DA12568

ACRONYM: DA

MEDLINETA: J Acquir Immune Defic Syndr

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