HIV Evolution and Escape.

HIV Evolution and Escape. Research Abstract Details 

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HIV Evolution and Escape. Abstract Text:

Douglas D Richman,Susan J Little,Davey M Smith,Terri Wrin,Christos Petropoulos,Joseph K Wong,

Human immunodeficiency virus (HIV) exemplifies the principles of Darwinian evolution with a telescoped chronology. Because of its high mutation rate and remarkably high rates of replication, evolution can be appreciated over periods of days in contrast to the durations conceived of by Darwin. Certain selective pressures that drive the evolution of HIV include chemotherapy, anatomic compartmentalization and the immune response. Examples of these selective forces on HIV evolution are described.

HIV Evolution and Escape. Publishing Authors By Initials

DD Richman,SJ Little,DM Smith,T Wrin,C Petropoulos,JK Wong,

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HIV Evolution and Escape. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Transactions of the American Clinical and Climatol

VOLUME: 115

Page Numbers: 289-303

Journal Abbreviation: Trans. Am. Clin. Climatol. Ass

ISSN: 0065-7778

DAY: 24

MONTH: 10

YEAR: 2004

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LANGUAGE: eng

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Grant and Affiliation Information for HIV Evolution and Escape.

AFFILIATION: Veterans Affairs San Diego Healthcare System, San Diego, CA 92161.

Country: United States

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MEDLINETA: Trans Am Clin Climatol Assoc

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