Hit and Lead identification: efficient practices for drug discovery.

Hit and Lead identification: efficient practices for drug discovery. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Hit and Lead identification: efficient practices for drug discovery. Abstract Text:

Robert A Goodnow,Paul Gillespie,

Hit and Lead identification: efficient practices for drug discovery. Publishing Authors By Initials

RA Goodnow,P Gillespie,

For similar investigative techniques: technology, pharmaceutical research abstracts see: investigative techniques: technology, pharmaceutical research

PUBMED ID PMID:

MEDLINE DATE:

Hit and Lead identification: efficient practices for drug discovery. Journal Published:

PUBLICATION TYPE: Review

Journal: Progress in medicinal chemistry

VOLUME: 45

Page Numbers: 1-61

Journal Abbreviation:

ISSN: 0079-6468

DAY: 19

MONTH: 11

YEAR: 2007

Hit and Lead identification: efficient practices for drug discovery. Information

Number of References: 250

LANGUAGE: eng

NlmUniqueID: 376452

Hit and Lead identification: efficient practices for drug discovery. Keywords Mesh Terms:

KEYWORDS: Technology, Pharmaceutical

MESH TERMS: methods

Chemical & Substance for Abstract: Hit and Lead identification: efficient practices for drug discovery. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Hit and Lead identification: efficient practices for drug discovery.

AFFILIATION: Discovery Chemistry, Roche Research Center, Nutley, NJ 07110-1199, USA.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Prog Med Chem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Hit and Lead identification: efficient practices for drug discovery Related Publications

• "Looking south to find the medicine of my heart".
• A mechanism for active hearing.
• Adequate subtotal gastric resection for duodenal ulcer.
• Alterations to network of NO/cGMP-responsive interstitial cells induced by outlet obstruction in guinea-pig bladder.
• Case of adolescent with Paget-Schroetter syndrome and underlying thrombophilia due to an elevated lipoprotein (A).
• Chk1 is required for G2/M checkpoint response induced by the catalytic topoisomerase II inhibitor ICRF-193.
• Collaborative research, knowledge and emergence.
• Collapsing Self/Other positions: identification through differentiation.
• Damage to the bladder neck alters autonomous activity and its sensitivity to cholinergic agonists.
• Dietary practices, dining out behavior, and physical activity correlates of weight loss maintenance.
• Graduate students take to the field in K-12 education.
• History of Arrythmia - Basketball: 1036: May 31 8:20 AM - 8:40 AM.
• Hit and Lead identification: efficient practices for drug discovery.
• Hospital pandemic preparedness: health care workers' opinions on working during a pandemic.
• Hypertension in the light of recent investigation.
• Idiopathic post-traumatic dermatitis at the site of recent joint replacement.
• Isolation and molecular characterisation of Neospora caninum in cattle in New Zealand.
• More data, fewer shifts: Molecular insights into the evolution of the spinning apparatus in non-orb-weaving spiders.
• Nuclear protein-induced bending and flexing of the hypoxic response element of the rat vascular endothelial growth factor promoter.
• Partial hepatectomy with intrahepatic cholangiojejunostomy; a useful addition to technical methods for the management of common duct stricture.
• Percutaneous versus surgical tracheotomy: an updated meta-analysis.
• Physical exam and occult post-traumatic vascular lesions: implications for the evaluation and management of arterial injuries in modern warfare in the endovascular era.
• Preparing and retaining high quality science and mathematics teachers: Research, programs and results.
• Progesterone levels and litter performance of sows following postpartum administration of prostaglandin F(2alpha).
• Sequence-specific oxidative base modifications in hypoxia-inducible genes.
• Steric selectivity in Na channels arising from protein polarization and mobile side chains.
• Stochastic simulation of chemical kinetics.
• The effect of protein dielectric coefficient on the ionic selectivity of a calcium channel.
• The significance of congenital lumbo-sacral abnormalities.
• Tuberculosis: evolution in millennia and minutes.