Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity.

Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity. Research Abstract Details 

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Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity. Abstract Text:

Masaru Kojima,Naoya Nakamura,Kazuhiko Shimizu,Masahumi Nishikawa,Morio Matsumoto,Keiko Higuchi,Nobuo Yamane,Norihumi Tsukamoto,Yoshio Tamaki,Hiroshi Inagaki,

Primary mucosa-associated lymphoid tissue (MALT) type lymphoma arising in the oral cavity is rare. We examined histopathologic, immunohistological and genotypic findings of seven cases of intraoral MALT lymphoma using formalin-fixed paraffin-embedded tissues. Histologically, two variants have been delineated. (i) In four cases of minor salivary gland type, the lymphoid follicles were surrounded by centrocyte-like (CCL) cells with occasional follicular colonization. The CCL cells invaded the residual salivary gland duct resulting in a lymphoepithelial lesion. CCL cells frequently showed plasmacytic differentiation. (ii) In three cases of follicular growth type, the lesion was characterized by follicular growth pattern resulting from prominent follicular colonization. CCL cells showed minimal plasma cell differentiation. There was no residual epithelial component detected even by cytokeratin immunostaining. There were no Epstein-Barr virus-encoded small RNA-positive cells detected by in situ hybridization. API2-MALT1 fusion transcript does not appear to be associated with either histological variant of primary intraoral MALT lymphoma.

Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity. Publishing Authors By Initials

M Kojima,N Nakamura,K Shimizu,M Nishikawa,M Matsumoto,K Higuchi,N Yamane,N Tsukamoto,Y Tamaki,H Inagaki,

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Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pathology oncology research : POR

VOLUME: 13

Page Numbers: 345-9

Journal Abbreviation: Pathol. Oncol. Res.

ISSN: 1219-4956

DAY: 25

MONTH: 12

YEAR: 2007

Histopathological Variation of Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Oral Cavity. Information

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LANGUAGE: eng

NlmUniqueID: 9706087

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AFFILIATION: Department of Pathology and Clinical Laboratories, Gunma Cancer Center Hospital, Ohta, 373-8550, Japan. mkojima@gunma-cc.jp.

Country: England

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MEDLINETA: Pathol Oncol Res

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