Histologic oddities at the porta hepatis in biliary atresia.

Histologic oddities at the porta hepatis in biliary atresia. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Histologic oddities at the porta hepatis in biliary atresia. Abstract Text:

PURPOSE: Highly unusual histologic findings at the porta hepatis in 3 infants who underwent Kasai portoenterostomy for biliary atresia are reported. METHODS: Portoenterostomy was performed using a standard operative technique. Serial transverse sections of the excised portal plate were examined by light microscopy along with sections from the distal extrahepatic biliary remnants, gallbladder, and liver biopsy. RESULTS: Of 61 consecutive infants who underwent Kasai portoenterostomy for biliary atresia, 3 were found to have highly unusual histologic features at the porta hepatis. All had type 3 biliary atresia. Two had hilar biliary ductules lined in part by squamous epithelium, and the third had a focus of mature hyaline cartilage surrounded by perichondrium adjacent to biliary ductules. In each case, these unusual histologic features were localized to the porta hepatis in the region of the transected portal plate. CONCLUSIONS: The presence of hyaline cartilage at the portal plate is likely to be an expression of defective morphogenesis, thus supporting the concept of disordered embryogenesis in the etiology of biliary atresia. Squamous epithelium within biliary ductules might also reflect a similar mechanism but could alternatively be an unusual metaplastic response to inflammation at this site.

Histologic oddities at the porta hepatis in biliary atresia. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Histologic oddities at the porta hepatis in biliary atresia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of pediatric surgery

VOLUME: 43

Page Numbers: 1328-32

Journal Abbreviation: J. Pediatr. Surg.

ISSN: 1531-5037

DAY: 21

MONTH: Jul

YEAR: 2008

Histologic oddities at the porta hepatis in biliary atresia. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 52631

Histologic oddities at the porta hepatis in biliary atresia. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Histologic oddities at the porta hepatis in biliary atresia. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Histologic oddities at the porta hepatis in biliary atresia.

AFFILIATION: Department of Histopathology, St. James's University Hospital, Leeds, UK.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Pediatr Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Histologic oddities at the porta hepatis in biliary atresia Related Publications

• A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea.
• A critical look at Lean Thinking in healthcare.
• A method of predicting workload and staffing level for radiotherapy treatment planning as plan complexity changes.
• Auricular erythema with nodules and scale.
• Bacillary angiomatosis in an HIV-positive man with multiple risk factors: A clinical and epidemiological puzzle.
• Chronic diarrhoea with weight loss.
• Cracking the junction: update on the progress of gastrointestinal absorption enhancement in the delivery of poorly absorbed drugs.
• Deriving evidence theoretical functions in multivariate data spaces: a systematic approach.
• Does treatment with 17 alpha-hydroxyprogesterone caproate increase the risk of gestational diabetes mellitus?
• Evaluation of in vitro virulence characteristics of the genus Pandoraea in lung epithelial cells.
• Histologic oddities at the porta hepatis in biliary atresia.
• Lip muscle reflex and intentional response levels in a simple speech task.
• Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol.
• Occupational head-butting and skin nodules.
• PROFESSIONAL FEES.
• Purification of vaccine lymph.
• Riot-control agents: personal experience.
• [Preparation, standardization and use of a desiccated, stable and purified smallpox vaccine.]