Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling.

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Research Abstract Details 

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Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Abstract Text:

Estelle ,Qian Hu,Ei-ichi Negishi,

Iteration of a Pd-catalyzed reaction of alkynyl- and oligoynylzincs with (E)-ICH=CHCl followed by metalation-termination with electrophiles(E) has provided a linear route to conjugated tri- and tetraynes, and Pd-catalyzed monoalkynylation of 1,1-dibromoenynes accompanied by dehydrobromination has provided a convergent route to conjugated tri- , tetra- , and pentaynes. Both display unprecedented high efficiency and selectivity. [reaction: see text]

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Publishing Authors By Initials

E ,Q Hu,E Negishi,

For similar inorganic chemicals: elements: metals, heavy: palladium research abstracts see: inorganic chemicals: elements: metals, heavy: palladium research

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Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Organic letters

VOLUME: 8

Page Numbers: 5773-6

Journal Abbreviation: Org. Lett.

ISSN: 1523-7060

DAY: 7

MONTH: Dec

YEAR: 2006

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Information

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LANGUAGE: eng

NlmUniqueID: 100890393

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Keywords Mesh Terms:

KEYWORDS: Palladium

MESH TERMS: chemistry

Chemical & Substance for Abstract: Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling. Information

Substance Name: Palladium

Registry Number: 7440-05-3

Grant and Affiliation Information for Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling.

AFFILIATION: Herbert C. Brown Laboratories of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM 36792

ACRONYM: GM

MEDLINETA: Org Lett

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