High surface area of porous silicon drives desorption of intact molecules.

High surface area of porous silicon drives desorption of intact molecules. Research Abstract Details 

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High surface area of porous silicon drives desorption of intact molecules. Abstract Text:

Trent R Northen,Hin-Koon Woo,Michael T Northen,Anders ,Winnie Uritboonthail,Kimberly L Turner,Gary Siuzdak,Trent R Northen,Hin-Koon Woo,Michael T Northen,Anders ,Winnie Uritboonthail,Kimberly L Turner,Gary Siuzdak,

The surface structure of porous silicon used in desorption/ionization on porous silicon (DIOS) mass analysis is known to play a primary role in the desorption/ionization (D/I) process. In this study, mass spectrometry and scanning electron microscopy (SEM) are used to examine the correlation between intact ion generation with surface ablation and surface morphology. The DIOS process is found to be highly laser energy dependent and correlates directly with the appearance of surface ions (Si(n)(+) and OSiH(+)). A threshold laser energy for DIOS is observed (10 mJ/cm(2)), which supports that DIOS is driven by surface restructuring and is not a strictly thermal process. In addition, three DIOS regimes are observed that correspond to surface restructuring and melting. These results suggest that higher surface area silicon substrates may enhance DIOS performance. A recent example that fits into this mechanism is the surface of silicon nanowires, which has a high surface energy and concomitantly requires lower laser energy for analyte desorption.

High surface area of porous silicon drives desorption of intact molecules. Publishing Authors By Initials

TR Northen,HK Woo,MT Northen,A ,W Uritboonthail,KL Turner,G Siuzdak,TR Northen,HK Woo,MT Northen,A ,W Uritboonthail,KL Turner,G Siuzdak,

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High surface area of porous silicon drives desorption of intact molecules. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Society for Mass Spectrome

VOLUME: 18

Page Numbers: 1945-9

Journal Abbreviation: J. Am. Soc. Mass Spectrom.

ISSN: 1044-0305

DAY: 22

MONTH: 08

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 9010412

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Grant and Affiliation Information for High surface area of porous silicon drives desorption of intact molecules.

AFFILIATION: Center for Mass Spectrometry, The Scripps Research Institute, La Jolla, California 92037, USA.

Country: United States

AGENCY: United States NIMH

GRANT: P30 MH062261-07

ACRONYM: MH

MEDLINETA: J Am Soc Mass Spectrom

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