High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo.

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Abstract Text:

Yu Chen,Peter M Andrews,Aaron D Aguirre,Joseph M Schmitt,James G Fujimoto,

Optical coherence tomography (OCT) is an emerging medical imaging technology that enables high-resolution, noninvasive, cross-sectional imaging of microstructure in biological tissues in situ and in real time. When combined with small-diameter catheters or needle probes, OCT offers a practical tool for the minimally invasive imaging of living tissue morphology. We evaluate the ability of OCT to image normal kidneys and discriminate pathological changes in kidney structure. Both control and experimental preserved rat kidneys were examined ex vivo by using a high-resolution OCT imaging system equipped with a laser light source at 1.3-microm wavelength. This system has a resolution of 3.3 microm (depth) by 6 microm (transverse). OCT imaging produced cross-sectional and en face images that revealed the sizes and shapes of the uriniferous tubules and renal corpuscles. OCT data revealed significant changes in the uriniferous tubules of kidneys preserved following an ischemic or toxic (i.e., mercuric chloride) insult. OCT data was also rendered to produce informative three-dimensional (3-D) images of uriniferous tubules and renal corpuscles. The foregoing observations suggest that OCT can be a useful non-excisional, real-time modality for imaging pathological changes in donor kidney morphology prior to transplantation.

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Publishing Authors By Initials

Y Chen,PM Andrews,AD Aguirre,JM Schmitt,JG Fujimoto,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: tomography: tomography, optical: tomography, optical coherence research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: tomography: tomography, optical: tomography, optical coherence research

PUBMED ID PMID:

MEDLINE DATE:

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of biomedical optics

VOLUME: 12

Page Numbers: 034008

Journal Abbreviation:

ISSN: 1083-3668

DAY: 3

MONTH: 12

YEAR: 2007

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9605853

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Keywords Mesh Terms:

KEYWORDS: Tomography, Optical Coherence

MESH TERMS: methods

Chemical & Substance for Abstract: High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo.

AFFILIATION: Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Cambridge, Massachusetts 02139, USA. chen_yu@mit.edu

Country: United States

AGENCY: United States NEI

GRANT: R01-EY11289-21

ACRONYM: EY

MEDLINETA: J Biomed Opt

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo Related Publications

• A 12 month in vivo study on the response of bone to a hydroxyapatite-polymethylmethacrylate cranioplasty composite.
• Asian ethnicity is associated with reduced pregnancy outcomes after assisted reproductive technology.
• Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s.
• Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons.
• Cinnamylindoline derivatives: synthesis and factor Xa (FXa) inhibitory activities.
• Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates.
• Developmental status of Aquatic Animal Experiment Facility, Aquatic Habitat (AQH), for International Space Station.
• Differentiation of gastric surface mucous cells (GSM06) induced by air-liquid interface is regulated partly through mitogen-activated protein kinase pathway.
• Diode-pumped, high-average-power femtosecond Cr(3+):LiCAF laser.
• Effective two-color SNP typing based on photoligation.
• Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second.
• Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver.
• High-dose vitamins E and C supplementation prevents ribavirin-induced hemolytic anemia in patients with chronic hepatitis C.
• High-resolution line-scanning optical coherence microscopy.
• High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo.
• Measuring dietary acculturation in Japanese Americans with the use of confirmatory factor analysis of food-frequency data.
• Molecular cloning and functional characterization of a prolactin-releasing peptide homolog from Xenopus laevis.
• New beamline optics for the effective use of a wiggler beam.
• PC-based rehabilitation tool for the elderly.
• Parallel processable light-driven DNA logic gate.
• Paraneoplastic dermatosis suspected of being Bazex syndrome in a woman with breast cancer.
• Percutaneous radiofrequency ablation and transcatheter arterial chemoembolization for hypervascular hepatocellular carcinoma: rate and risk factors for local recurrence.
• Phase-sensitive optical coherence tomography at up to 370,000 lines per second using buffered Fourier domain mode-locked lasers.
• Photochemical synthesis of R-shaped DNA via 5-cyanovinyldeoxyuridine.
• Photochemical transition of 5-methylcytosine to thymine by DNA photoligation.
• Polyester non-woven fabric finger cover as a TRUCT Braille reading assistance tool for Braille learners.
• Quantitative retention of membrane lipids in the freeze-fracture replica.
• Sequence specific interstrand photocrosslinking for effective SNP typing.
• The hydrogen bonding and amino-imino tautomerization of the alkoxy-aminopyridines and amino-methoxypyrimidines with acetic acid The effects of the methoxy group.
• Ultralow-threshold Kerr-lens mode-locked Ti:Al(2)O(3) laser.