High-resolution dynamic imaging of contrast agent uptake in a beating heart.

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Abstract Text:

Dan Xu,Zhi-Pei Liang,Yijen Wu,T Kevin Hitchens,Chien Ho,

Dynamic contrast-enhanced (DCE) MR cardiac imaging has been recognized as a unique and powerful tool for assessing both cardiac functions and physiological conditions of the heart tissues (e.g., tissue rejection following heart transplantation). However, because of cardiac motion and the limited data acquisition speed of existing MRI techniques, it has been very difficult to acquire dynamic images of very high spatiotemporal resolution. This paper proposes a new generalized series (GS) based imaging technique to overcome this challenging problem. Specifically, the proposed technique collects two data sets: a) a sequence of highresolution reference images over several cardiac cycles using a gated cine acquisition scheme before the injection of a contrast agent (or a molecular probe), and b) a sequence of reduced data sets with very high frame rate during the transient wash-in/wash-out stage of the contrast agent. A GS model is then used to combine these two data sets to reconstruct a high-resolution image sequence, capturing both the cardiac motions and dynamic signal changes due to the interaction of the contrast agent with the cardiac tissues. The proposed technique has been validated using both simulated and experimental data, which show that high-resolution dynamic images can be acquired with as few as 8 encodings (in contrast to 256 encodings required in the traditional Fourier transform-based methods). The technique provides a very effective tool for physiological imaging of the beating heart with molecular probes.

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Publishing Authors By Initials

D Xu,ZP Liang,Y Wu,T Kevin Hitchens,C Ho,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Conference proceedings : ... Annual International

VOLUME: 7

Page Numbers: 7397-400

Journal Abbreviation:

ISSN: 1557-170X

DAY: 6

MONTH: 02

YEAR: 2005

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101243413

High-resolution dynamic imaging of contrast agent uptake in a beating heart. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: High-resolution dynamic imaging of contrast agent uptake in a beating heart. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for High-resolution dynamic imaging of contrast agent uptake in a beating heart.

AFFILIATION: Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Conf Proc IEEE Eng Med Biol So

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

High-resolution dynamic imaging of contrast agent uptake in a beating heart Related Publications

• Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction.
• Ageing and ART: a waste of time and money?
• An in vitro model of morphine withdrawal manifests the enhancing effect on human immunodeficiency virus infection of human T lymphocytes through the induction of substance P.
• Apigenin suppresses cancer cell growth through ERbeta.
• Bandgap-assisted surface-plasmon sensing.
• Characterization of mucins in human middle ear and Eustachian tube.
• Characterization of the mouse Muc3 membrane bound intestinal mucin 5' coding and promoter regions: regulation by inflammatory cytokines.
• Cloning and characterization of mouse intestinal MUC3 mucin: 3' sequence contains epidermal-growth-factor-like domains.
• Concurrent laparoscopic right hemicolectomy and ultra-low anterior resection with colonic J-pouch anal anastomosis for synchronous carcinoma.
• Coordinated Muc2 and Muc3 mucin gene expression in Trichinella spiralis infection in wild-type and cytokine-deficient mice.
• Developmental estrogen exposures predispose to prostate carcinogenesis with aging.
• Directing macromolecular conformation through halogen bonds.
• Directly measured insulin resistance and the assessment of clustered cardiovascular risks in hypertension.
• Does certificate of need affect cardiac outcomes and costs?
• Effects of lipid association on lomustine (CCNU) administered intracerebrally to syngeneic 36B-10 rat brain tumors.
• Expression of mucins in mucoid otitis media.
• Feasibility of weekly HIV drug delivery to enhance drug localization in lymphoid tissues based on pharmacokinetic models of lipid-associated indinavir.
• Health-seeking patterns among Chinese immigrant patients enrolled in the directly observed therapy program in New York City.
• High-resolution dynamic imaging of contrast agent uptake in a beating heart.
• MRI detection of macrophages labeled using micrometer-sized iron oxide particles.
• Methamphetamine-induced behavioral sensitization in mice: alterations in mu-opioid receptor.
• Natural killer cell inhibits human immunodeficiency virus replication in chronically infected immune cells.
• Orientation of deoxyhemoglobin at high magnetic fields: structural insights from RDCs in solution.
• Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress.
• Repression of the hindbrain developmental program by Cdx factors is required for the specification of the vertebrate spinal cord.
• Spectroscopic evaluation of human tear lipids.
• Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
• Theoretical investigation of the mechanisms of reactions of H2CN and H2SiN with NO.
• Treatments of multi-invasive giant prolactinoma.
• Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.