High prevalence of aeroallergen sensitization among infants of atopic parents.

High prevalence of aeroallergen sensitization among infants of atopic parents. Research Abstract Details 

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High prevalence of aeroallergen sensitization among infants of atopic parents. Abstract Text:

Grace K LeMasters,Kimberly Wilson,Linda Levin,Jocelyn Biagini,Patrick Ryan,James E Lockey,Sherry Stanforth,Stephanie Maier,Jun Yang,Jeff Burkle,Manuel Villareal,Gurjit K Khurana Hershey,David I Bernstein,Grace K LeMasters,Kimberly Wilson,Linda Levin,Jocelyn Biagini,Patrick Ryan,James E Lockey,Sherry Stanforth,Stephanie Maier,Jun Yang,Jeff Burkle,Manuel Villareal,Gurjit K Khurana Hershey,David I Bernstein,

OBJECTIVE: To present methodology to identify atopic parents and determine the prevalence of sensitization to 15 aeroallergens in their infant offspring. STUDY DESIGN: A birth cohort of infants was identified from birth records; an infant was enrolled if 1 of the parents reported allergy respiratory symptoms and had a positive skin prick test (SPT) to a common aeroallergen. At age 1 year, these infants were tested to the same aeroallergens. RESULTS: Of the 680 enrolled infants, 28.4% were SPT+ to 1 or more aeroallergens and/or food, and 18.0% were positive to 1 or more aeroallergens. By category of allergens, 9.7% were sensitized to pollens, 7.5% to molds, 4.3% to house dust mite and/or cockroach, and 3.4% to dog and/or cat. Of the infants who were positive to an aeroallergen, 65.7% remained positive at age 2 years. CONCLUSIONS: Infants born to atopic parents with percutaneous sensitization to aeroallergens are at increased risk for aeroallergen sensitization during infancy, which persists to age 2 years. These findings suggest that current clinical practices, which generally avoid skin testing before age 2 years, be reassessed in this population of high-risk children.

High prevalence of aeroallergen sensitization among infants of atopic parents. Publishing Authors By Initials

GK LeMasters,K Wilson,L Levin,J Biagini,P Ryan,JE Lockey,S Stanforth,S Maier,J Yang,J Burkle,M Villareal,GK Khurana Hershey,DI Bernstein,GK LeMasters,K Wilson,L Levin,J Biagini,P Ryan,JE Lockey,S Stanforth,S Maier,J Yang,J Burkle,M Villareal,GK Khurana Hershey,DI Bernstein,

For similar diagnosis: diagnostic techniques and procedures: skin tests research abstracts see: diagnosis: diagnostic techniques and procedures: skin tests research

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High prevalence of aeroallergen sensitization among infants of atopic parents. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: The Journal of pediatrics

VOLUME: 149

Page Numbers: 505-11

Journal Abbreviation: J. Pediatr.

ISSN: 0022-3476

DAY: 3

MONTH: Oct

YEAR: 2006

High prevalence of aeroallergen sensitization among infants of atopic parents. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 375410

High prevalence of aeroallergen sensitization among infants of atopic parents. Keywords Mesh Terms:

KEYWORDS: Skin Tests

MESH TERMS: immunology

Chemical & Substance for Abstract: High prevalence of aeroallergen sensitization among infants of atopic parents. Information

Substance Name: Allergens

Registry Number: 0

Grant and Affiliation Information for High prevalence of aeroallergen sensitization among infants of atopic parents.

AFFILIATION: Department of Environmental Health, Division of Epidemiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Grace.LeMasters@uc.edu

Country: United States

AGENCY: United States NIEHS

GRANT: ES11170

ACRONYM: ES

MEDLINETA: J Pediatr

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