High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array.

High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array. Research Abstract Details 

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High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array. Abstract Text:

Xiaochen Xu,Lei Sun,Jonathan M Cannata,Jesse T Yen,K Kirk Shung,

In this paper, we report the development of the first high-frequency (HF) pulsed-wave Doppler system using a 30-MHz linear array transducer to assess the cardiovascular functions in small animals. This array-based pulsed-wave Doppler system included a 16-channel HF analog beamformer, a HF pulsed-wave Doppler module, timing circuits, HF bipolar pulsers and analog front ends. The beamformed echoes acquired by the 16-channel analog beamformer were fed directly to the HF pulsed-wave Doppler module. Then the in-phase and quadrature-phase (IQ) audio Doppler signals were digitized by either a sound card or a Gage digitizer and stored in a personal computer. The Doppler spectrogram was displayed on a personal computer in real time. The two-way beamwidths were determined to be 160 mum to 320 mum when the array was electronically focused at different focal points at depths from 5 to 10 mm. A micro-flow phantom, consisting of a polyimide tube with an inner diameter of 127 mum and the wire phantom were used to evaluate and calibrate the system. The results show that the system is capable of detecting motion velocity of the wire phantom as low as 0.1 mm/s, and detecting blood-mimicking flow velocity in the 127-mum tube lower than 7 mm/s. The system was subsequently used to measure the blood flow in vivo in two mouse abdominal superficial vessels, with diameters of approximately 200 mum, and a mouse aorta close to the heart. These results demonstrated that this system may become an indispensable part of the current HF array-based imaging systems for small animal studies. (E-mail: xiaochenxu@gmail.com).

High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array. Publishing Authors By Initials

X Xu,L Sun,JM Cannata,JT Yen,KK Shung,

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High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Ultrasound in medicine & biology

VOLUME: 34

Page Numbers: 638-46

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ISSN: 0301-5629

DAY: 12

MONTH: 11

YEAR: 2007

High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array. Information

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LANGUAGE: eng

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Grant and Affiliation Information for High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array.

AFFILIATION: NIH Resource on Medical Ultrasonic Transducer Technology, Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.

Country: England

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MEDLINETA: Ultrasound Med Biol

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