High density cultivation of BSK cells on sintered alumina ceramic foam support.

High density cultivation of BSK cells on sintered alumina ceramic foam support. Research Abstract Details 

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High density cultivation of BSK cells on sintered alumina ceramic foam support. Abstract Text:

A perfusion system which utilizes a porous ceramic core has been tested for the cultivation of transformed BHK cells which produce human transferrin. A design is presented in which cells are immobilized within the porous ceramic particle and are fed by continuous perfusion of batch liquid medium. It was found that more than 5 x 10(9) BHK cells could be supported within the 40 mL ceramic matrix, a ten-fold increase in cell density per unit surface area over the standard roller bottle cultures or a five-fold increase in volumetric cell density over suspension cultures. The cell specific productivity of human transferrin was similar to that observed in suspension culture. The system offer the advantages of significant reduction in serum requirements and the potential for scale-up.

High density cultivation of BSK cells on sintered alumina ceramic foam support. Publishing Authors By Initials

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High density cultivation of BSK cells on sintered alumina ceramic foam support. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Cytotechnology

VOLUME: 5

Page Numbers: 233-41

Journal Abbreviation: Cytotechnology

ISSN: 0920-9069

DAY: 9

MONTH: Mar

YEAR: 1991

High density cultivation of BSK cells on sintered alumina ceramic foam support. Information

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LANGUAGE: eng

NlmUniqueID: 8807027

High density cultivation of BSK cells on sintered alumina ceramic foam support. Keywords Mesh Terms:

KEYWORDS: Transferrin

MESH TERMS: biosynthesis

Chemical & Substance for Abstract: High density cultivation of BSK cells on sintered alumina ceramic foam support. Information

Substance Name: Glucose

Registry Number: 50-99-7

Grant and Affiliation Information for High density cultivation of BSK cells on sintered alumina ceramic foam support.

AFFILIATION: Department of Chemical Engineering Biotechnology Lab, U.B.C., Vancouver, Canada.

Country: NETHERLANDS

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MEDLINETA: Cytotechnology

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