Hierarchy of metabolic compounds based on their synthesising capacity.

Hierarchy of metabolic compounds based on their synthesising capacity. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Hierarchy of metabolic compounds based on their synthesising capacity. Abstract Text:

T Handorf,O ,D Kahn,R Heinrich,

The concept of scopes is applied to analyse large metabolic networks. Scopes are defined as sets of metabolites that can be synthesised by a metabolic network when it is provided with given seeds (Sets of initial metabolic compounds). Thus, scopes represent synthesising capacities of the seeds in the network. A hierarchy is discussed in the sense that compounds, which are part of the scope of another compound, possess scopes themselves that are subsets of the former scope. This hierarchy is analysed by means of a directed acyclic graph. Using a simple chemical model, it is found that this hierarchy contains specific structures that can, to a large extent, be explained by the chemical composition of the participating compounds. In this way, it represents a new kind of map of metabolic networks, arranging the metabolic compounds according to their chemical capacity.

Hierarchy of metabolic compounds based on their synthesising capacity. Publishing Authors By Initials

T Handorf,O ,D Kahn,R Heinrich,

For similar information science: computing methodologies: software: user-computer interface research abstracts see: information science: computing methodologies: software: user-computer interface research

PUBMED ID PMID:

MEDLINE DATE:

Hierarchy of metabolic compounds based on their synthesising capacity. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Systems biology

VOLUME: 153

Page Numbers: 359-63

Journal Abbreviation:

ISSN: 1741-2471

DAY: 7

MONTH: Sep

YEAR: 2006

Hierarchy of metabolic compounds based on their synthesising capacity. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101232067

Hierarchy of metabolic compounds based on their synthesising capacity. Keywords Mesh Terms:

KEYWORDS: User-Computer Interface

MESH TERMS: physiology

Chemical & Substance for Abstract: Hierarchy of metabolic compounds based on their synthesising capacity. Information

Substance Name: Proteins

Registry Number: 0

Grant and Affiliation Information for Hierarchy of metabolic compounds based on their synthesising capacity.

AFFILIATION: Department of Theoretical Biophysics, Institute of Biology, Humboldt University, Ivalidenstr. 42, 10115 Berlin, Germany. Thomashandorf@gmx.de

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Syst Biol (Stevenage)

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Hierarchy of metabolic compounds based on their synthesising capacity Related Publications

• A prospective study on the association between hay fever among children and incidence of asthma in East Germany.
• Allergic sensitization to cat in childhood as major predictor of incident respiratory allergy in young adults.
• Candles, dishwashers and Alzheimer's disease.
• Cycling power output produced during flat and mountain stages in the Giro d'Italia: a case study.
• Dare to share: a unique approach to presenting and publishing.
• Day care in relation to respiratory-tract and gastrointestinal infections in a German birth cohort study.
• Direct NMR analysis of cannabis water extracts and tinctures and semi-quantitative data on Delta(9)-THC and Delta(9)-THC-acid.
• Evaluation of a sampling strategy for estimation of long-term PM2.5 exposure for epidemiological studies.
• Expansion of signal transduction networks.
• FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248).
• Flory radius of polymers in a periodic field: An exact analytic theory.
• Hierarchy of metabolic compounds based on their synthesising capacity.
• High prevalence of pneumonia in children of a smelter town.
• Muscarinic excitation in grasshopper song control circuits is limited by acetylcholinesterase activity.
• Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach.
• Power Output during the Tour de France.
• Ravens judge competitors through experience with play caching.
• Reviews of three books on medicinal plants from India.
• Second-order QCD corrections to the thrust distribution in electron-positron annihilation.
• Social factors, allergen, endotoxin, and dust mass in mattress.
• The stress of relocation and neuropeptides: an epidemiological study in children.
• Timing of Solid Food Introduction in Relation to Eczema, Asthma, Allergic Rhinitis, and Food and Inhalant Sensitization at the Age of 6 Years: Results From the Prospective Birth Cohort Study LISA.
• Weight change, weight cycling and mortality in the ERFORT Male Cohort Study.
• [BLOOD PRESSURE REGISTRATIONS AFTER MEDICATION WITH 1-P-CHLOROPHENYL-2,3-DIMETHYL-4-DIMETHYLAMINO-2-BUTANOL HCL.]
• [CONTINUOUS ELECTROCARDIOGRAPHIC RECORDINGS AFTER MEDICATION WITH 1-P-CHLOROPHENYL-2,3-DIMETHYL-4-DIMETHYLAMINO-2-BUTANOL HCL.]
• [Cardiotocography]
• [Counselling, treatment and aftercare of cancer patients by the family physician]
• [Not Available.]
• [Not Available.]
• [On the etiology and microbiology of actinomycosis. IV. On the sensitivity of Actinobacillus actinomycetem-comitans to the usual antibiotics and sulfonamides in vitro. (A contribution to the antibiotic therapy of actinomycosis in man)]