Pyrimidines

- 1,3-diacyl derivatives of imidazolidine and hexahydropyrimidine. 1. Preparation by novel method and characterization.

- 1,3-diacyl derivatives of imidazolidine and hexahydropyrimidine. 2. Antimycotic activity.

- 5-DIAZOURACIL (NSC-23519): A PHASE I STUDY.

- Alopecia areata treated with topical minoxidil. A 1% minoxidil topical solution was used to treat 48 patients with alopecia areata, ie, 24 patients with patchy disease and 24 patients with alopecia totalis...

- Azaribine in the treatment of psoriasis. A low dose, double-blind evaluation.

- B-vitamins and the biosyntheses of purines and pyrimidines.

- c-Abl kinase regulates curcumin-induced cell death through activation of c-Jun N-terminal kinase. Curcumin, a natural phenolic compound found in turmeric (Curcuma longa) exhibits anticancer properties, attributed to its antiproliferative and...

- Chronic myelogenous leukemia and myeloproliferative disease. In Section I, Dr. Stephen O'Brien reviews the latest data on the clinical use of imatinib (STI571, Gleevec, Glivec) in CML. His review focuses on the use of...

- Clinical and haemodynamic study of minoxidil in moderately hypertensive patients. 1. We have evaluated the effectiveness and safety of minoxidil in moderately hypertensive out-patients. Eight patients were treated with hydrochlorothiazide...

- Clinical benefit of intermittent administration of imatinib in a patient with metastatic gastrointestinal stromal tumour. Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours of the gastrointestinal tract, resistant to conventional chemotherapy and radiotherapy, but...

- CLINICAL EFFECTS OF PROLONGED (CONTINUOUS) INFUSION OF STREPTONIGRIN (NSC-45383) IN ADVANCED CANCER.

- Clinical evaluation of 4-propylamino-1H-pyrazolo [3,4-d]pyrimidine (NSC-4928).

- DARAPRIM in malaria.

- Defining and managing imatinib resistance. While imatinib is highly effective therapy, with improving prospects over time for sustained remission and potential to severely limit or eliminate disease...

- Dihydropyrimidinase deficiency, a progressive neurological disorder? A case of a child presenting with congenital abnormalities at birth is reported. The early development remained severely retarded and acquired skills...

- EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.

- Enhancement of the effects of 5-fluorouracil.

- Epigenetic control of MAGE gene expression by the KIT tyrosine kinase. The Class I MAGE proteins include the MAGE-A, MAGE-B, and MAGE-C antigens, which are normally expressed only in male germ cells but may be aberrantly...

- Expeditious access to the most easily ionized closed-shell molecule, W2(hpp)4. A new synthetic path, far superior to either of those previously available, to the W2(hpp)4 molecule (Hhpp =...

- Experimental studies with a new antiviral agent.