Vitamin B 12

- 2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis. OBJECTIVE: To investigate the distribution of the A2756G polymorphism of the methionine synthase reductase (MTR) gene in patients with rheumatoid arthritis...

- 5'-Peroxyadenosine and 5'-peroxyadenosylcobalamin as intermediates in the aerobic photolysis of adenosylcobalamin. The photolysis of adenosylcobalamin (coenzyme B12) results in homolytic cleavage of the Co-C5' bond, forming cob(II)alamin and the 5'-deoxyadenosyl radical....

- A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia. We have identified a patient with methylmalonic aciduria and homocystinuria due to a defect in cobalamin metabolism of the cb1C type mutant. At the time of...

- A DEAE cellulose column method using predosed 57Co cyanocobalamin and pooled serum for measuring vitamin B12 in serum.

- A family study of chronic gastritis. Histological, immunological and functional aspects.

- A new method for the assay of vitamin B12 by TLC.

- A NEW METHOD OF ESTIMATING GLOMERULAR-FILTRATION RATE: USE OF DIMINISHING BLOOD CONCENTRATION OF LABELLED VITAMIN B12.

- A relationship between intestinal bacteria and the absorption of vitamin B12 in rats with diverticula of the small bowel.

- A simple, convenient method to synthesize cobalamins: synthesis of homocysteinylcobalamin, N-acetylcysteinylcobalamin, 2-N-acetylamino-2-carbomethoxyethanethiolatocobalamin, sulfitocobalamin and nitrocobalamin. Glutathionylcobalamin, nitrocobalamin and sulfitocobalamin are important cobalamin metabolites isolable from human tissues. Herein we demonstrate that a...

- A statement of homocyst(e)ine and cardiovascular disease.

- A vitamin-B12 preparation with retarded absorption.

- Absorption of vitamin B12 in pancreatic insufficiency.

- Absorption of vitamin B12 in tobacco amblyopia.

- Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects. Plasma total homocysteine concentrations (tHcy) are a putative risk factor for CVD. Tea is a rich dietary source of polyphenols and caffeine, both of which...

- Amelioration of autonomic neuropathy by methylcobalamin in uremics on hemodialysis.

- Analogues, ageing and aberrant assimilation of vitamin B12 in Alzheimer's disease. Vitamin B12 assimilation might be disrupted in patients with Alzheimer's disease. We therefore measured B12 carrier protein saturation and inactive B12...

- Analysis of the Cob(II)alamin-5'-deoxy-3',4'-anhydroadenosyl radical triplet spin system in the active site of diol dehydrase. A triplet spin system (S=1) is detected by low-temperature electron paramagnetic resonance (EPR) spectroscopy in samples of diol dehydrase and the functional...

- Assay of serum vitamin B12 using an isotope method. The Schilling test.

- Assay of vitamin B12 in blood. A simple method.

- Assessment of early and delayed responses in vitamin B12 absorption during antibiotic therapy in tropical malabsorption. 1. Vitamin B12 absorption was measured in 18 patients with tropical malabsorption. 2. Absorption was particularly impaired in patients with severe mucosal...