Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure.

Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Research Abstract Details 

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Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Abstract Text:

T Harano,T Yamaguchi,E Kimoto,

The effect of intracellular Ca2+ on high pressure-induced hemolysis of human erythrocytes was examined. Red cells were incubated with Ca2+ (0.01-1 mM) in the presence of ionophore A23187. The Ca(2+)-loaded cells were subjected to a pressure of 200 mPa. Treatment with 0.1 mM Ca2+ had the greatest suppressive effect on the hemolysis. On removal of intracellular Ca2+, red cells showed a morphological change from echinocytes to normal discocytes but the hemolysis remained unaltered. Measurement of intracellular K+ and viscosity demonstrated that the suppressive effect of Ca2+ on the hemolysis is irreversible and is largely associated with the increase of intracellular viscosity induced by K+ efflux.

Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Publishing Authors By Initials

T Harano,T Yamaguchi,E Kimoto,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 116

Page Numbers: 773-7

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Oct

YEAR: 1994

Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure. Information

Substance Name: Sodium Chloride

Registry Number: 7647-14-5

Grant and Affiliation Information for Hemolytic properties of Ca(2+)-treated human erythrocytes under hydrostatic pressure.

AFFILIATION: Department of Chemistry, Faculty of Science, Fukuoka University.

Country: JAPAN

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MEDLINETA: J Biochem

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