Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia.

Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Research Abstract Details 

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Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Abstract Text:

Angiotensin converting enzyme inhibitor (ACE-I) treated hypertensive patients are well known to be at risk during general anesthesia, because of hypotension that can occur. We compared hemodynamic changes in these patients during induction of general anesthesia with propofol and etomidate - two intravenous anesthetics. Hypotension after propofol that we observed in ACE-I group versus normotension after etomidate (p < 0.001) in our opinion may be the result of additive effect of similar endothelium-dependent mechanism of action of propofol and ACE-I, i.e. increase in production and release of nitric oxide (NO). This very unique observation, however, needs further investigation to precisely define the mechanism of our finding.

Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Publishing Authors By Initials

For similar organic chemicals: phenols: propofol research abstracts see: organic chemicals: phenols: propofol research

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Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Pharmacological reports : PR

VOLUME: 57

Page Numbers: 675-8

Journal Abbreviation: Pharmacol Rep

ISSN: 1734-1140

DAY: 28

MONTH: 05

YEAR: 2008

Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Information

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LANGUAGE: eng

NlmUniqueID: 101234999

Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Keywords Mesh Terms:

KEYWORDS: Propofol

MESH TERMS: surgery

Chemical & Substance for Abstract: Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia. Information

Substance Name: Enalapril

Registry Number: 75847-73-3

Grant and Affiliation Information for Hemodynamic effect of propofol in enalapril-treated hypertensive patients during induction of general anesthesia.

AFFILIATION: Emergency Department, Medical University of Bia?ystok, Waszyngtona 15A, PL 15-274 Bia?ystok, Poland. mzaprzalka@poczta.onet.pl

Country: Poland

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MEDLINETA: Pharmacol Rep

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