[Heme synthesis and iron status in pregnancy]

[Heme synthesis and iron status in pregnancy] Research Abstract Details 

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[Heme synthesis and iron status in pregnancy] Abstract Text:

In 130 pregnant women (41 without complications, 40 with prematurity, 49 with EPH-Gestosis) Serumferritin, ferrochelatase (FCH), delta-aminolaevulinic-aciddehydratase (D-ALA-D), porphobilinogendeaminase (PBG-D) as well as hematologic routine parameters were measured. Regarding serumferritin, both uncomplicated and cases with pathologic conditions revealed a significant decrease in group II (28th week of pregnancy) as compared to group I (12th to 28th week of pregnancy). Women with EPH-Gestosis showed the lowest values. Activities of hemesynthesizing enzymes did not show any significant differences, neither between the two groups nor between uncomplicated and pathologic cases. Compared to healthy, non pregnant women; in pregnant women we found a significant increase in D-ALA-D and PBG-D, but a significant decrease in FCH. Enzyme pattern in pregnancy reveals an increased synthesis of porphobilinogen and an increased conversion of porphobilinogen to porphyrin. The low activity of FCH we measured in our study could be a reason for the elevation of free protoporphyrin in the erythrocytes.

[Heme synthesis and iron status in pregnancy] Publishing Authors By Initials

For similar female urogenital diseases and pregnancy complications: pregnancy complications: pregnancy complications, hematologic research abstracts see: female urogenital diseases and pregnancy complications: pregnancy complications: pregnancy complications, hematologic research

PUBMED ID PMID:

MEDLINE DATE:

[Heme synthesis and iron status in pregnancy] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta medica Austriaca. Supplement

VOLUME: 6

Page Numbers: 368-72

Journal Abbreviation:

ISSN: 0303-8181

DAY: 26

MONTH: 02

YEAR: 1979

[Heme synthesis and iron status in pregnancy] Information

Number of References:

LANGUAGE: ger

NlmUniqueID: 7502262

[Heme synthesis and iron status in pregnancy] Keywords Mesh Terms:

KEYWORDS: Pregnancy Complications, Hematologic

MESH TERMS: enzymology

Chemical & Substance for Abstract: [Heme synthesis and iron status in pregnancy] Information

Substance Name: Ferrochelatase

Registry Number: EC 4.99.1.1

Grant and Affiliation Information for [Heme synthesis and iron status in pregnancy]

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Country: AUSTRIA

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MEDLINETA: Acta Med Austriaca Suppl

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