Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications.

Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Research Abstract Details 

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Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Abstract Text:

Mari A Watanabe,

INTRODUCTION: The aim of this study was to see whether heart rate turbulence (HRT) parameters change preceding imminent ventricular tachyarrhythmias (VT/VF). METHODS AND RESULTS: The Spontaneous Ventricular Tachyarrhythmia Database (Medtronic Version 1.0) consisting of 83 paired (control and pre-VT/VF) sets of 1,000 RR intervals recorded by the Medtronic Jewel Plus ICD was used. Sixty-one control records and 69 pre-VT/VF records had two or more ectopic beats, allowing calculation of six HRT indices: means and standard deviations (SD) of turbulence slope (TS), turbulence onset (TO), and turbulence timing (TT). The only index found to be different between control and pre-VT/VF records was SD of TS (4.2 +/- 3.0 control vs 3.1 +/- 1.9 pre-VT/VF, P < 0.05). Thirty-one datasets classified as having normal HRT in control demonstrated a decrease of both TS mean (P < 0.01) and SD (P < 0.01), and loss of correlation between TS mean and left ventricular ejection fraction (LVEF) preceding VT/VF (P < 0.0001 control, P = 0.8 pre-VT/VF). CONCLUSION: Both mean and SD of TS are reduced before VT/VF, but only in patients who have normal baseline HRT, and are capable of manifesting reduction. This may be why previous studies could not agree on pre-arrhythmia characteristics.

Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Publishing Authors By Initials

MA Watanabe,

For similar cardiovascular diseases: heart diseases: arrhythmias, cardiac: tachycardia: tachycardia, ventricular research abstracts see: cardiovascular diseases: heart diseases: arrhythmias, cardiac: tachycardia: tachycardia, ventricular research

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Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of cardiovascular electrophysiology

VOLUME: 17

Page Numbers: 735-40

Journal Abbreviation: J. Cardiovasc. Electrophysiol.

ISSN: 1045-3873

DAY: 3

MONTH: Jul

YEAR: 2006

Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Information

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LANGUAGE: eng

NlmUniqueID: 9010756

Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. Keywords Mesh Terms:

KEYWORDS: Tachycardia, Ventricular

MESH TERMS: therapy

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Grant and Affiliation Information for Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications.

AFFILIATION: Internal Medicine Department, Munich University of Technology, Munich, Germany. watanabe@slu.edu

Country: United States

AGENCY: United States NHLBI

GRANT: 2T32 HL07374-19

ACRONYM: HL

MEDLINETA: J Cardiovasc Electrophysiol

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