Health-related quality of life in veterans and nonveterans with HIV/AIDS.

Health-related quality of life in veterans and nonveterans with HIV/AIDS. Research Abstract Details 

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Health-related quality of life in veterans and nonveterans with HIV/AIDS. Abstract Text:

Joseph M Mrus,Anthony C Leonard,Michael S Yi,Susan N Sherman,Shawn L Fultz,Amy C Justice,Joel Tsevat,

PURPOSE: To compare health-related quality of life (HRQoL) between patients receiving care in Veterans Administration (VA) settings (veterans) and non-VA settings (nonveterans), and to explore determinants of HRQoL and change in HRQoL over time in subjects living with HIV/AIDS. SUBJECTS: One hundred veterans and 350 nonveterans with HIV/AIDS from 2 VA and 2 university-based sites in 3 cities interviewed in 2002 to 2003 and again 12 to 18 months later. METHODS: We assessed health status (functional status and symptom bother), health ratings, and health values (time tradeoff [TTO] and standard gamble [SG] utilities). We also explored bivariate and multivariable associations of HRQoL measures with a number of demographic, clinical, spiritual/religious, and psychosocial characteristics. RESULTS: Compared with nonveterans, the veteran population was older (47.7 vs 42.0 years) and consisted of a higher proportion of males (97% vs 83%), of participants with a history of injection drug use (23% vs 15%), and of subjects with unstable housing situations (14% vs 6%; P<.05 for all comparisons). On scales ranging from 0 (worst) to 100 (best), veterans reported significantly poorer overall function (mean [SD]; 65.9 [17.2] vs 71.9 [16.8]); lower rating scale scores (67.6 [21.7] vs 73.5 [21.0]), lower TTO values (75.7 [37.4] vs 89.0 [23.2]), and lower SG values (75.0 [35.8] vs 83.2 [28.3]) than nonveterans (P<.05 for all comparisons); however, in multivariable models, veteran status was only a significant determinant of SG and TTO values at baseline. Among other determinants that were associated with multiple HRQoL outcomes in baseline and follow-up multivariable analyses were: symptom bother, overall function, religiosity/spirituality, depressive symptoms, and financial worries. CONCLUSIONS: Veterans reported significantly poorer HRQoL than nonveterans, but when controlling for other factors, veteran status was only a significant determinant of TTO and SG health values at baseline. Correlates of HRQoL such as symptom bother, spirituality/religiosity, and depressive symptoms could be fruitful potential targets for interventions to improve HRQoL in patients with HIV/AIDS.

Health-related quality of life in veterans and nonveterans with HIV/AIDS. Publishing Authors By Initials

JM Mrus,AC Leonard,MS Yi,SN Sherman,SL Fultz,AC Justice,J Tsevat,

For similar persons: veterans research abstracts see: persons: veterans research

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Health-related quality of life in veterans and nonveterans with HIV/AIDS. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of general internal medicine : official jo

VOLUME: 21 Suppl 5

Page Numbers: S39-47

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ISSN: 1525-1497

DAY: 3

MONTH: Dec

YEAR: 2006

Health-related quality of life in veterans and nonveterans with HIV/AIDS. Information

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LANGUAGE: eng

NlmUniqueID: 8605834

Health-related quality of life in veterans and nonveterans with HIV/AIDS. Keywords Mesh Terms:

KEYWORDS: Veterans

MESH TERMS: statistics & numerical data

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Grant and Affiliation Information for Health-related quality of life in veterans and nonveterans with HIV/AIDS.

AFFILIATION: Cincinnati VA Medical Center, Cincinnati, OH, USA. joemrus@hotmail.com

Country: United States

AGENCY: United States NIAID

GRANT: U01 AI25897

ACRONYM: AI

MEDLINETA: J Gen Intern Med

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