[Gynecologic neoplasms in pregnancy]

[Gynecologic neoplasms in pregnancy] Research Abstract Details 

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[Gynecologic neoplasms in pregnancy] Abstract Text:

R A Steiner,

Cancer in pregnancy represents a complicated scenario and a unique challenge to the pregnant patient, her family and the physicians. Extraordinary decisions are forced upon the woman and all participants involved with her care. They must address medical, religions, social, ethical and emotional concerns of the mother and her family. Because of the low incidence of malignant disease in pregnancy it is not possible to develop a large personal experience. The most common malignancies in pregnancy are cancers of the cervix and the breast, followed by melanomas and ovarian cancer. After stratification for stage all gynaecological malignancies have a similar prognosis as cancers in nonpregnant patients, provided they are treated correctly. The general principle is to treat the cancer and to allow the pregnancy to proceed until adequate foetal maturity has been achieved. In cervical cancer a delay in therapy of several weeks revealed no adverse effects on treatment outcome. Generally caesarean section should be the delivery method of choice. In breast cancer diagnoses is typically delayed for 5 to 7 months for various reasons. Therefore work-up of a mass discovered during pregnancy has to be as strict and complete as outside pregnancy. Breast-conservation therapy remains an option even in pregnancy but adjuvant radiotherapy should be started after the child has been born. Even chemotherapy is possible although the first trimester is the most critical time resulting in a 10-20% malformation rate as compared with a rate of 3% in the general population. Chemotherapy in the second and third trimester may result in intrauterine growth restriction. Breast feeding is contraindicated in women receiving chemotherapy. Therapeutic abortion does not improve survival. Most ovarian cancers diagnosed in pregnancy are of low grade and early stage (Stage I). Work-up and treatment involving surgery and chemotherapy follows the same guidelines as in the nonpregnant woman. In order to arrive at the optimal decision, the patient and her family have to be optimally informed.

[Gynecologic neoplasms in pregnancy] Publishing Authors By Initials

RA Steiner,

For similar neoplasms: pregnancy complications, neoplastic research abstracts see: neoplasms: pregnancy complications, neoplastic research

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[Gynecologic neoplasms in pregnancy] Journal Published:

PUBLICATION TYPE: Review

Journal: Therapeutische Umschau. Revue thérapeutique

VOLUME: 56

Page Numbers: 616-23

Journal Abbreviation:

ISSN: 0040-5930

DAY: 12

MONTH: Oct

YEAR: 1999

[Gynecologic neoplasms in pregnancy] Information

Number of References: 24

LANGUAGE: ger

NlmUniqueID: 407224

[Gynecologic neoplasms in pregnancy] Keywords Mesh Terms:

KEYWORDS: Pregnancy Complications, Neoplastic

MESH TERMS: therapy

Chemical & Substance for Abstract: [Gynecologic neoplasms in pregnancy] Information

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Grant and Affiliation Information for [Gynecologic neoplasms in pregnancy]

AFFILIATION: Kantonales Frauenspital Fontana, Chur.

Country: SWITZERLAND

AGENCY:

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ACRONYM:

MEDLINETA: Ther Umsch

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