Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Abstract Text:

Shugeng Cao,Peggy J Brodie,James S Miller,Fidy Ratovoson,Chris Birkinshaw,Sennen Randrianasolo,Etienne Rakotobe,Vincent E Rasamison,David G I Kingston,

Bioassay-guided fractionation of the ethanol extract obtained from the fruits of Rheedia calcicola led to the isolation of two new guttiferone analogues, guttiferones K (1) and L (16-hydroxyguttiferone K) (2). The structures of 1 and 2 were established on the basis of extensive interpretation of one- and two-dimensional NMR spectroscopic data. Both compounds were tested for their antiproliferative activity against the A2780 human ovarian cancer cell line.

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Publishing Authors By Initials

S Cao,PJ Brodie,JS Miller,F Ratovoson,C Birkinshaw,S Randrianasolo,E Rakotobe,VE Rasamison,DG Kingston,

For similar plants: plants, medicinal research abstracts see: plants: plants, medicinal research

PUBMED ID PMID:

MEDLINE DATE:

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of natural products

VOLUME: 70

Page Numbers: 686-8

Journal Abbreviation:

ISSN: 0163-3864

DAY: 10

MONTH: 03

YEAR: 2007

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7906882

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Keywords Mesh Terms:

KEYWORDS: Plants, Medicinal

MESH TERMS: chemistry

Chemical & Substance for Abstract: Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest. Information

Substance Name: guttiferone L

Registry Number: 0

Grant and Affiliation Information for Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.

AFFILIATION: Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

Country: United States

AGENCY: United States FIC

GRANT: U01 TW000313

ACRONYM: TW

MEDLINETA: J Nat Prod

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest Related Publications

• A clinical trial of an antidepressant, tranylcy-promine ("Parnate").
• A not so Pacific voyage: the 'floating laboratory' of Nicolas Baudin.
• Antiplasmodial activity of compounds from Sloanea rhodantha (Baker) Capuron var. rhodantha from the Madagascar rain forest.
• Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1).
• Antiproliferative cardenolides of an Elaeodendron sp. from the Madagascar rain forest(1).
• Antiproliferative prenylated stilbenes and flavonoids from Macaranga alnifolia from the Madagascar rainforest.
• Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.
• Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation.
• Cytotoxic Cardenolide Glycosides of Roupellina (Strophanthus) boivinii from the Madagascar Rainforest.
• Cytotoxic clerodane diterpenoids and their hydrolysis products from Casearia nigrescens from the rainforest of Madagascar.
• Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign.
• Cytotoxic compounds of Schizolaena hystrix from the Madagascar rainforest.
• Cytotoxic triterpenoid saponins of Albizia gummifera from the Madagascar rain forest.
• DNase I Footprint Analysis of Protein-DNA Binding.
• Direct analysis of RNA after transfection.
• Effectiveness of chiropractic treatment for infantile colic.
• Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
• Fund raising: innovative fund raising brings art to a hospital.
• Furoquinoline alkaloids of Ertela (Monnieria) trifolia (L.) Kuntze from the Suriname rainforest.
• Gene regulation in the postgenomic era: technology takes the wheel.
• Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.
• Homology-driven chromatin remodeling by human RAD54.
• Human ACF1 alters the remodeling strategy of SNF2h.
• Independent and complementary methods for large-scale structural analysis of mammalian chromatin.
• Ipomoeassin F, a new cytotoxic macrocyclic glycoresin from the leaves of Ipomoea squamosa from the Suriname rainforest.
• Preparation of poly(a)(+) RNA.
• Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation.
• Shifting adaptive landscapes: progress and challenges in reconstructing early hominid environments.
• Tambouranolide, a new cytotoxic hydroxybutanolide from a Tambourissa sp. (Monimiaceae).
• The shape of things to come: structural and synthetic studies of taxol and related compounds.