Global experiences with vardenafil in men with erectile dysfunction and underlying conditions.

Global experiences with vardenafil in men with erectile dysfunction and underlying conditions. Research Abstract Details 

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Global experiences with vardenafil in men with erectile dysfunction and underlying conditions. Abstract Text:

Objective: Vardenafil has demonstrated efficacy for the pharmacological management of erectile dysfunction (ED). Accumulating evidence suggests that ED is frequently associated with underlying cardiovascular and metabolic conditions which are thought to be involved in the aetiology of ED. The present review aims to summarise and discuss the available evidence for the efficacy, safety and tolerability of vardenafil in patients with underlying conditions including diabetes, hypertension and dyslipidaemia. Methods: Relevant articles were identified through a PubMed search of clinical trials and postmarketing surveillance studies of vardenafil in patients with ED including those with diabetes, hypertension and dyslipidaemia. Results: Across all trials, vardenafil showed good efficacy for the treatment of ED in patients with diabetes, hypertension and dyslipidaemia. Vardenafil also showed a favourable safety and tolerability profile. The concomitant use of medication to treat hypertension or dyslipidaemia was not associated with an increase in adverse events following vardenafil treatment. Conclusions: The prevalence of both diagnosed and undiagnosed underlying conditions is high among men with ED. The evidence presented in this review suggests that vardenafil is efficacious and well tolerated in patients with ED and diabetes, hypertension and/or dyslipidaemia and can be recommended as first-line treatment for ED in patients with these conditions.

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Global experiences with vardenafil in men with erectile dysfunction and underlying conditions. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International journal of clinical practice

VOLUME: 62

Page Numbers: 1594-603

Journal Abbreviation: Int. J. Clin. Pract.

ISSN: 1742-1241

DAY: 29

MONTH: Oct

YEAR: 2008

Global experiences with vardenafil in men with erectile dysfunction and underlying conditions. Information

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LANGUAGE: eng

NlmUniqueID: 9712381

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Grant and Affiliation Information for Global experiences with vardenafil in men with erectile dysfunction and underlying conditions.

AFFILIATION: Pyrah Department of Urology, St James's University Hospital, Leeds, UK.

Country: England

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MEDLINETA: Int J Clin Pract

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