Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition.

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Abstract Text:

L J Moran,M Noakes,P M Clifton,G Wittert,L Tomlinson,C Galletly,N Luscombe,L Tomlinson,R J Norman,

Background - Polycystic ovary syndrome (PCOS) is a common endocrine condition in women of reproductive age. In subjects with PCOS, there may be dysregulation of ghrelin, a hormone implicated in appetite regulation. The effect of varying dietary composition on ghrelin is unclear. Objective - To examine the effects of PCOS status and varying diet composition on ghrelin homeostasis and subjective measures of satiety and hunger. Design - Overweight BMI-matched women (BMI 35.4 +/-0.9 kgm(-2)) followed a standard protein (55% carbohydrate, 15% protein) (n = 10 PCOS, n = 6 non-PCOS) or high protein diet (40% carbohydrate, 30% protein) (n =10 PCOS, n = 5 non-PCOS) for 12 weeks of weight loss (about 6000 kJ/day) and 4 weeks of energy balance. Post-prandial ghrelin and measures of hunger and satiety by visual analogue scores (VAS) were assessed after a representative meal tolerance test (MTT). Outcomes - Diet composition had no effect on ghrelin or VAS measures. Non-PCOS subjects had a 70% higher fasting baseline ghrelin (P = 0.011) and a greater increase in fasting ghrelin (57.5% vs 34.0%, P = 0.033) and a greater maximal decrease in MTT ghrelin with weight loss (-42.7 +/- 17.3 vs -8.5 +/- 4.1 pM, P=0.02) than subjects with PCOS. Subjects with PCOS were more hungry (P =0.001) and less satiated (P = 0.007) at week 0 and 16 than non-PCOS subjects. Conclusions - Ghrelin homeostasis and measures of hunger and satiety are significantly impaired in subjects with PCOS but not affected by diet composition.

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Publishing Authors By Initials

LJ Moran,M Noakes,PM Clifton,G Wittert,L Tomlinson,C Galletly,N Luscombe,L Tomlinson,RJ Norman,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Asia Pacific journal of clinical nutrition

VOLUME: 12 Suppl

Page Numbers: S52

Journal Abbreviation:

ISSN: 0964-7058

DAY: 16

MONTH: 03

YEAR: 2003

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9440304

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition.

AFFILIATION: Reproductive Medicine Unit, Dept Obstetrics and Gynaecology, University of Adelaide, SA 5000.

Country: Australia

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Asia Pac J Clin Nutr

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition Related Publications

• A brief review of the history and use of the daresbury ;miyake' monochromator for surface science.
• Abdominal aortic aneurysm: pathogenesis and implications for management.
• Association between AMPD1 gene polymorphism and coagulation factors in patients with coronary heart disease.
• Association between osteopontin and human abdominal aortic aneurysm.
• Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
• Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.
• Conservative mutageneic perturbations of amino acids connecting helix 12 in the 1alpha,25(OH)2-D3 receptor (VDR) to the ligand cause significant transactivational effects.
• Design and synthesis of quinolin-2(1H)-one derivatives as potent CDK5 inhibitors.
• Dopamine dysregulation syndrome: implications for a dopamine hypothesis of bipolar disorder.
• Dry period length in US Jerseys: characterization and effects on performance.
• Effect of unitization on associative recognition in amnesia.
• Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition.
• Homocysteine and abdominal aortic aneurysms.
• How basic is basic science?
• It all make sense: biomedical knowledge, causal connections and memory in the novice diagnostician.
• Minireview: vitamin D receptor: new assignments for an already busy receptor.
• New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model.
• Physical Activity Intensity and Duration Patterns in Mild-to-Moderately Depressed Adults: 2434: Board #113 June 1 3:30 PM -5:00 PM.
• Preterm labour. Cervical function and prematurity.
• Quality management systems in ART: are they really needed? An Australian clinic's experience.
• Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.
• Structure-activity relationship (SAR) investigations of substituted imidazole analogs as TRPV1 antagonists.
• Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors.
• Successful breastfeeding after discharge of preterm and sick newborn infants.
• Teaching session C: data collection and statistics in radiotherapy : size matters.
• The role of biomedical knowledge in diagnosis of difficult clinical cases.
• The use of anti-mullerian hormone in predicting menstrual response after weight loss in overweight women with polycystic ovary syndrome.
• Unscheduled incorporation of thymidine in ultraviolet-irradiated human lymphocytes.
• Vs03 abdominal aortic aneurysm: insight into pathogenesis, biomarkers and targets for medical therapy.
• Within-herd heritability estimated with daughter-parent regression for yield and somatic cell score.