Genotyping of samples lacking expected antibodies in ABO blood group.

Genotyping of samples lacking expected antibodies in ABO blood group. Research Abstract Details 

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Genotyping of samples lacking expected antibodies in ABO blood group. Abstract Text:

Zhi-Hui Deng,Jian-Qiang Zeng,Qiong Yu,Yu-Qing Su,Yan-Lian Liang,Liang Lu,Wei-Gang Zhu,Bao-Cheng Yang,Zhi-Hui Deng,Jian-Qiang Zeng,Qiong Yu,Yu-Qing Su,Yan-Lian Liang,Liang Lu,Wei-Gang Zhu,Bao-Cheng Yang,

We report nine donations with ABO inconsistency in reverse typing caused by partly or entirely missing antibodies. A and B antigens and antibodies were examined by serological blood typing, and ABO deoxyribonucleic acid (DNA) analyses were performed by sequence-specific priming and sequencing. A B101 allele was demonstrable in a case with O phenotype. The molecular mechanisms in deficiency of natural ABO antibody could be partly clarified. The ABO genotyping technique is an accurate method for determining the blood samples involved in ABO grouping discrepancies and is a valuable complement to serology for correct determination of donor blood status. The mechanisms involved in the absence of potent natural antibodies directed against A and B antigen lacking on an individual's own red cell membranes remain to be further investigated. J. Clin. Lab. Anal. 21:363-366, 2007. (c) 2007 Wiley-Liss, Inc.

Genotyping of samples lacking expected antibodies in ABO blood group. Publishing Authors By Initials

ZH Deng,JQ Zeng,Q Yu,YQ Su,YL Liang,L Lu,WG Zhu,BC Yang,ZH Deng,JQ Zeng,Q Yu,YQ Su,YL Liang,L Lu,WG Zhu,BC Yang,

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Genotyping of samples lacking expected antibodies in ABO blood group. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of clinical laboratory analysis

VOLUME: 21

Page Numbers: 363-6

Journal Abbreviation: J. Clin. Lab. Anal.

ISSN: 0887-8013

DAY: 27

MONTH: 11

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 8801384

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Grant and Affiliation Information for Genotyping of samples lacking expected antibodies in ABO blood group.

AFFILIATION: ShenZhen Institute of Transfusion Medicine, ShenZhen, GuangDong, China.

Country: United States

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MEDLINETA: J Clin Lab Anal

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