Genetics of metabolic syndrome.

Genetics of metabolic syndrome. Research Abstract Details 

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Genetics of metabolic syndrome. Abstract Text:

Metabolic syndrome (MetS) is a common phenotype, affecting about 24% of the US population. It is associated with an increased risk for type 2 diabetes and cardiovascular disease. Although there is no universally accepted definition for MetS, affected individuals commonly have a cluster of features, including abdominal obesity, hypertension, dyslipidemia, and dysglycemia. Recently, there has been extensive interest in potential genetic contributions to MetS. At present, no single gene or cluster of genes has been consistently replicated for MetS among different populations, likely due to the complex interplay between gene and environment necessary for expression of this phenotype. We review recent studies regarding the genetic contributions to MetS.

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PUBLICATION TYPE: Journal Article

Journal: Current diabetes reports

VOLUME: 8

Page Numbers: 141-8

Journal Abbreviation: Curr. Diab. Rep.

ISSN: 1539-0829

DAY: 30

MONTH: Apr

YEAR: 2008

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LANGUAGE: eng

NlmUniqueID: 101093791

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Grant and Affiliation Information for Genetics of metabolic syndrome.

AFFILIATION: Blackburn Cardiovascular Genetics Laboratory, Scientist, Vascular Biology Research Group, Robarts Research Institute, 406 - 100 Perth Drive, London, Ontario N6A 5K8, Canada.E-mail: hegele@robarts.ca.

Country: United States

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MEDLINETA: Curr Diab Rep

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