Genetic predictors of acute and chronic pain.

Genetic predictors of acute and chronic pain. Research Abstract Details 

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Genetic predictors of acute and chronic pain. Abstract Text:

Robert R Edwards,

Although broad agreement exists that genetic factors are important contributors to individual differences in pain sensitivity and risk for developing painful clinical conditions, the field of pain genetics is still in its infancy. This article reviews recent human studies of the genetics of acute and chronic pain, which implicate polymorphisms in genes coding for catechol-O-methyltransferase activity and micro-opioid receptors, among a number of others, as influential in explaining variability among the pain responses of individuals. Growing interest in pain genetics and accelerating methodologic advances in the field will almost certainly alter our understanding of which genes contribute to nociception and how dynamic interactions between multiple genes and environmental events shape the human experience of pain.

Genetic predictors of acute and chronic pain. Publishing Authors By Initials

RR Edwards,

For similar proteins: membrane proteins: receptors, cell surface: receptors, g-protein-coupled: receptors, opioid: receptors, opioid, mu research abstracts see: proteins: membrane proteins: receptors, cell surface: receptors, g-protein-coupled: receptors, opioid: receptors, opioid, mu research

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Genetic predictors of acute and chronic pain. Journal Published:

PUBLICATION TYPE: Review

Journal: Current rheumatology reports

VOLUME: 8

Page Numbers: 411-7

Journal Abbreviation:

ISSN: 1523-3774

DAY: 3

MONTH: Dec

YEAR: 2006

Genetic predictors of acute and chronic pain. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100888970

Genetic predictors of acute and chronic pain. Keywords Mesh Terms:

KEYWORDS: Receptors, Opioid, mu

MESH TERMS: genetics

Chemical & Substance for Abstract: Genetic predictors of acute and chronic pain. Information

Substance Name: Catechol O-Methyltransferase

Registry Number: EC 2.1.1.6

Grant and Affiliation Information for Genetic predictors of acute and chronic pain.

AFFILIATION: Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer 1-108, Baltimore, MD 21287, USA. redwar10@jhmi.edu

Country: United States

AGENCY: United States NIAMS

GRANT: K23-AR051315

ACRONYM: AR

MEDLINETA: Curr Rheumatol Rep

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