[Genetic polymorphism of 6 short tandem repeat loci in Mongolian population of China]

[Genetic polymorphism of 6 short tandem repeat loci in Mongolian population of China] Research Abstract Details 

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[Genetic polymorphism of 6 short tandem repeat loci in Mongolian population of China] Abstract Text:

Dong-xia Li,Li-fu Bi,Xiu-lan Su,

OBJECTIVE: To clarify the distribution of genetic polymorphism of D3S1358, D13S317, D5S818, D6S1043, D2S1772, D7S3048 loci of the Mongolian population in Ximeng pastoral area and construct the relevant genetic database. METHODS: Multiplex PCR and polyacrylamide gel electrophoresis were used to investigate the polymorphism of 6 short tandem repeat (STR) loci in 286 individuals of the Mongolian population. RESULTS: In this study, 6, 9, 8, 11, 14, 11 alleles were observed at the 6 STR loci respectively. The genotypes distributions in Mongolian population were in accordance with Hardy-Weinberg equilibrium (P>0.05), the cumulative expected heterozygosities (H), discriminating probability (DP) and the polymorphism information contents (PIC) for the 6 loci were 0.9998, 09999, 0.9998 respectively. These data were compared with those of the Han population. The results showed there were significant difference in D3S1358, D13S317, D5S818, D2S1772, D7S3048 loci between the Mongolian population and Han population (P<0.05). However, no significant difference in D6S1043 locus was seen between the two populations (P>0.05). CONCLUSION: The results demonstrate that these 6 STR loci can serve as genetic marks and provide valuable data which are beneficial to studying the population genetics and ethnology.

[Genetic polymorphism of 6 short tandem repeat loci in Mongolian population of China] Publishing Authors By Initials

DX Li,LF Bi,XL Su,

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[Genetic polymorphism of 6 short tandem repeat loci in Mongolian population of China] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yix

VOLUME: 21

Page Numbers: 407-9

Journal Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Z

ISSN: 1003-9406

DAY: 9

MONTH: Aug

YEAR: 2004

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LANGUAGE: chi

NlmUniqueID: 9425197

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AFFILIATION: Molecular Biology Research Center of Inner Mongolian College, Huhehaote, Inner Mongolian Autonomous Region, 010059 PR China.

Country: China

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MEDLINETA: Zhonghua Yi Xue Yi Chuan Xue Z

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