Genetic heterogeneity in the VP7 of group C rotaviruses.

Genetic heterogeneity in the VP7 of group C rotaviruses. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Genetic heterogeneity in the VP7 of group C rotaviruses. Abstract Text:

Vito Martella, ,Eleonora Lorusso,Nicola Decaro,Anna Bellacicco,Costantina Desario,Marialaura Corrente,Grazia Greco,Paschalina Moschidou,Maria Tempesta,Serenella Arista,Max Ciarlet,Antonio Lavazza,Canio Buonavoglia,Vito Martella, ,Eleonora Lorusso,Nicola Decaro,Anna Bellacicco,Costantina Desario,Marialaura Corrente,Grazia Greco,Paschalina Moschidou,Maria Tempesta,Serenella Arista,Max Ciarlet,Antonio Lavazza,Canio Buonavoglia,Vito Martella, ,Eleonora Lorusso,Nicola Decaro,Anna Bellacicco,Costantina Desario,Marialaura Corrente,Grazia Greco,Paschalina Moschidou,Maria Tempesta,Serenella Arista,Max Ciarlet,Antonio Lavazza,Canio Buonavoglia,

Evidence for a possible zoonotic role of group C rotaviruses (GCRVs) has been recently provided. To gain information on the genetic relationships between human and animal GCRVs, we sequenced the VP7 gene of 10 porcine strains detected during a large surveillance study from different outbreaks of gastroenteritis in piglets. Four GCRV strains were genetically related to the prototype GCRV porcine Cowden strain. A completely new VP7 genotype included 4 strains (344/04-7-like) that shared 92.5% to 97.0% aa identity to each other, but <83% to human GCRVs and <79% to other porcine and bovine GCRVs. A unique 4-aa insertion (SSSV or SSTI), within a variable region at the carboxy-terminus of VP7, represented a distinctive feature for these 4 unique strains. An additional strain, 134/04-18, was clearly different from all human and animal GCRVs (<85% aa identity) and likely accounts for a distinct VP7 genotype. The VP7 of a unique strain, 42/05-21, shared similar ranges of aa sequence identities with porcine and human strains (88.0-90.7% to porcine GCRVs and 85.2-88.2% to human GCRVs). Plotting the VP7 gene of strain 42/05-21 against the VP7 of human and porcine strains revealed discontinuous evolution rates throughout the VP7 molecule, suggesting different mutational pressure or a remote intragenic recombination event. These findings provide the need for future epidemiological surveys and warrant studies to investigate the pathogenic potential of these novel GCRVs in pigs.

Genetic heterogeneity in the VP7 of group C rotaviruses. Publishing Authors By Initials

V Martella,K ,E Lorusso,N Decaro,A Bellacicco,C Desario,M Corrente,G Greco,P Moschidou,M Tempesta,S Arista,M Ciarlet,A Lavazza,C Buonavoglia,V Martella,K ,E Lorusso,N Decaro,A Bellacicco,C Desario,M Corrente,G Greco,P Moschidou,M Tempesta,S Arista,M Ciarlet,A Lavazza,C Buonavoglia,V Martella,K ,E Lorusso,N Decaro,A Bellacicco,C Desario,M Corrente,G Greco,P Moschidou,M Tempesta,S Arista,M Ciarlet,A Lavazza,C Buonavoglia,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Genetic heterogeneity in the VP7 of group C rotaviruses. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Virology

VOLUME: 367

Page Numbers: 358-66

Journal Abbreviation: Virology

ISSN: 0042-6822

DAY: 5

MONTH: 07

YEAR: 2007

Genetic heterogeneity in the VP7 of group C rotaviruses. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 110674

Genetic heterogeneity in the VP7 of group C rotaviruses. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Genetic heterogeneity in the VP7 of group C rotaviruses. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Genetic heterogeneity in the VP7 of group C rotaviruses.

AFFILIATION: Department of Animal Health and Wellbeing, Faculty of Veterinary Medicine of Bari, Valenzano, Bari, Italy. v.martella@veterinaria.uniba.it

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Virology

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER: EF464657

Number Hits: 0

Genetic heterogeneity in the VP7 of group C rotaviruses Related Publications

• A real-time PCR assay for detection and quantification of Mycoplasma agalactiae DNA.
• A study on the long-term immunity induced by La Sota strain of Newcastle disease virus grown in a BS/BEK cell line of bovine embryo kidney origin.
• Biological and genetic analysis of a bovine-like coronavirus isolated from water buffalo (Bubalus bubalis) calves.
• Canine adenoviruses and herpesvirus.
• Canine distemper virus.
• Caprine herpesvirus 1 vaccine with the LTK63 mutant as a mucosal adjuvant induces strong protection against genital infection in goats.
• Clinical protection against caprine herpesvirus 1 genital infection by intranasal administration of a live attenuated glycoprotein E negative bovine herpesvirus 1 vaccine.
• Comparison of methods for the detection of methicillin resistance in Staphylococcus aureus isolates from food products.
• Detection and molecular characterization of a canine norovirus.
• Detection and quantification of Anaplasma marginale DNA in blood samples of cattle by real-time PCR.
• Detection of a porcine-like rotavirus in a child with enteritis in Italy.
• Detection of bovine coronavirus using a TaqMan-based real-time RT-PCR assay.
• Detection of infectious canine parvovirus type 2 by mRNA real-time RT-PCR.
• Duplex real-time polymerase chain reaction for simultaneous detection and quantification of Anaplasma marginale and Anaplasma centrale.
• Epizootic abortion related to infections by Chlamydophila abortus and Chlamydophila pecorum in water buffalo (Bubalus bubalis).
• Evaluation of the Antigenic Relationships among Canine Parvovirus Type 2 Variants.
• Evidence for immunisation failure in vaccinated adult dogs infected with canine parvovirus type 2c.
• Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia.
• Genetic analysis of feline panleukopenia viruses from cats with gastroenteritis.
• Genetic heterogeneity in the VP7 of group C rotaviruses.
• Genetic heterogeneity of porcine enteric caliciviruses identified from diarrhoeic piglets.
• Identification of a porcine calicivirus related genetically to human sapoviruses.
• Norovirus in captive lion cub (Panthera leo).
• Potent inhibition of genital herpesvirus infection in goats by cidofovir.
• Respiratory disease associated with bovine coronavirus infection in cattle herds in Southern Italy.
• Severe outbreak of bovine coronavirus infection in dairy cattle during the warmer season.
• Specific identification of feline panleukopenia virus and its rapid differentiation from canine parvoviruses using minor groove binder probes.
• The study molecular epidemiology of canine parvovirus, Europe.
• Typing by polymerase chain reaction of buffalo rotaviruses isolated in Italy.
• Use of real-time RT-PCR as a rapid molecular approach for differentiation of field and vaccine strains of bluetongue virus serotypes 2 and 9.