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Genetic determination in onset age of wrist fracture.

Genetic determination in onset age of wrist fracture. Research Abstract Details 

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  • Genetic determination in onset age of wrist fracture. Abstract Text:

    donghai xiongDonghai Xiong,wei wangWei Wang,yuan chenYuan Chen,hui jiangHui Jiang,hong-wen dengHong-Wen Deng,

    The onset age of fracture may be useful to explore the clinical and genetic heterogeneity of fracture study. In the present study, we investigated the heritability of the onset age of wrist fracture (OAWF) in 30 female full-sib pairs. The phenotypic correlation coefficient of OAWF was 0.309 (P=0.09) for this cohort of female sib pairs, and the narrow-sense heritability (h2) was estimated to be 0.618 (P=0.09). In addition, the h2 derived from the variance component model implemented in SOLAR was 0.722 (P<0.05). This study, for the very first time, suggested that OAWF is under genetic control and thus potentially helps clarify genetic heterogeneity of wrist fracture.

    Genetic determination in onset age of wrist fracture. Publishing Authors By Initials

    d xiongD Xiong,w wangW Wang,y chenY Chen,h jiangH Jiang,hw dengHW Deng,

    For similar disorders of environmental origin: wounds and injuries: arm injuries: wrist injuries research abstracts see: disorders of environmental origin: wounds and injuries: arm injuries: wrist injuries research

    PUBMED ID PMID:

    MEDLINE DATE:

    Genetic determination in onset age of wrist fracture. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of human genetics

    VOLUME: 52

    Page Numbers: 481-4

    Journal Abbreviation: J. Hum. Genet.

    ISSN: 1434-5161

    DAY: 25

    MONTH: 04

    YEAR: 2007

    Genetic determination in onset age of wrist fracture. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9808008

    Genetic determination in onset age of wrist fracture. Keywords Mesh Terms:

    KEYWORDS: Wrist Injuries

    MESH TERMS: genetics

    Chemical & Substance for Abstract: Genetic determination in onset age of wrist fracture. Information

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    Grant and Affiliation Information for Genetic determination in onset age of wrist fracture.

    AFFILIATION: The Key Laboratory of Biomedical Information Engineering of the Ministry of Education and Institute of Molecular Genetics, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, People's Republic of China.

    Country: Japan

    Japan Research PublicationJapan Research Publication

    AGENCY: United States NIGMS

    GRANT: R01 GM60402-01A1

    ACRONYM: GM

    MEDLINETA: J Hum Genet

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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