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[Genetic background of preeclampsia]

[Genetic background of preeclampsia] Research Abstract Details 

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  • [Genetic background of preeclampsia] Abstract Text:

    agnieszka seremak-mrozikiewiczAgnieszka Seremak-Mrozikiewicz,krzysztof drewsKrzysztof Drews,agnieszka seremak-mrozikiewiczAgnieszka Seremak-Mrozikiewicz,krzysztof drewsKrzysztof Drews,

    Population studies have been suggesting genetic predisposition to the appearance of preeclampsia (PE) for a considerable period of time now. In familial occurrence of the disease higher frequency of preeclampsia has been observed in mothers, daughters and sisters of women burned of this poor medical history and higher risk to severe PE development. Although a single gene may contribute to the development of the patomechanizm of PE, most authors focus on the analysis of the common influence of candidate genes which are involved in a series of pathophysiological processes of PE. Thus, PE is often believed to be the final phenotype (increase of blood pressure and multiorgan complications development), being the result of intermediate phenotypes acting at the same time and being modulated by environmental factors. PE belongs to the complex human disease. The results of the findings connected with the contribution of maternal, paternal and fetal genotypes in PE development remain unclear, though a stronger influence of maternal genes, with a weaker influence of those transferred from the father, may be observed. Despite the existing divergences (the findings on the genetic background of PE are in conflict, no doubt due to the population differences and small number of investigated groups), the results obtained so far stress the necessity to discover the genetic risk factors as it may do both: facilitate the identification of groups of women predisposed to preeclampsia and allow for an early prophylactic administration.

    [Genetic background of preeclampsia] Publishing Authors By Initials

    a seremak-mrozikiewiczA Seremak-Mrozikiewicz,k drewsK Drews,a seremak-mrozikiewiczA Seremak-Mrozikiewicz,k drewsK Drews,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

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    [Genetic background of preeclampsia] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Ginekologia polska

    VOLUME: 78

    Page Numbers: 802-6

    Journal Abbreviation: Ginekol. Pol.

    ISSN: 0017-0011

    DAY: 18

    MONTH: Oct

    YEAR: 2007

    [Genetic background of preeclampsia] Information

    Number of References:

    LANGUAGE: pol

    NlmUniqueID: 374641

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    Grant and Affiliation Information for [Genetic background of preeclampsia]

    AFFILIATION: Klinika Perinatologii i Chorób Kobiecych Katedry Perinatologii i Ginekologii, Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu. asm@data.pl

    Country: Poland

    Poland Research PublicationPoland Research Publication

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    MEDLINETA: Ginekol Pol

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