Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2.

Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Research Abstract Details 

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Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Abstract Text:

Marsha A Wilcox,Zhong Li,Will Tapper,Sharon Browning,Karen Curtin,Jie Ding,Yuejing Ding,France Gagnon,Qimei He,Tai-Yue Kuo,Mingyao Li,George Matthew,Ling Mei,Shaoqi Rao,Jim Shaw,Zhi Wei,Zhaoxia Yu,Weihua Zhang,Tian Zheng,Guohua Zhu,

The papers in presentation group 2 of Genetic Analysis Workshop 15 (GAW15) conducted association analyses of rheumatoid arthritis data. The analyses were carried out primarily in the data provided by the North American Rheumatoid Arthritis Consortium (NARAC). One group conducted analyses in the data provided by the Canadian Rheumatoid Arthritis Genetics Study (CRAGS). Analysis strategies included genome-wide scans, the examination of candidate genes, and investigations of a region of interest on chromosome 18q21. Most authors employed relatively new methods, proposed extensions of existing methods, or introduced completely novel methods for aspects of association analysis. There were several common observations; a group of papers using a variety of methods found stronger association, on chromosomes 6 and 18 and in candidate gene PTPN22 among women with early onset. Generally, models that considered haplotypes or multiple markers showed stronger evidence for association than did single marker analyses.

Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Publishing Authors By Initials

MA Wilcox,Z Li,W Tapper,S Browning,K Curtin,J Ding,Y Ding,F Gagnon,Q He,TY Kuo,M Li,G Matthew,L Mei,S Rao,J Shaw,Z Wei,Z Yu,W Zhang,T Zheng,G Zhu,

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Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Genetic epidemiology

VOLUME: 31 Suppl 1

Page Numbers: S12-21

Journal Abbreviation: Genet. Epidemiol.

ISSN: 0741-0395

DAY: 6

MONTH: 12

YEAR: 2007

Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2. Information

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LANGUAGE: eng

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AFFILIATION: i3 Drug Safety, 950 Winter Street, Waltham, MA 02451, USA. Marsha.Wilcox@i3DrugSafety.com

Country: United States

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MEDLINETA: Genet Epidemiol

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