Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil.

Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil. Research Abstract Details 

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Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil. Abstract Text:

Yuki Kobayashi,Hiromi Okuda,Kana Nakamura,Go Sato,Takuya Itou,Adolorata A B Carvalho,Marlon V Silva,Carla S Mota,Fumio H Ito,Takeo Sakai,Yuki Kobayashi,Hiromi Okuda,Kana Nakamura,Go Sato,Takuya Itou,Adolorata A B Carvalho,Marlon V Silva,Carla S Mota,Fumio H Ito,Takeo Sakai,Yuki Kobayashi,Hiromi Okuda,Kana Nakamura,Go Sato,Takuya Itou,Adolorata A B Carvalho,Marlon V Silva,Carla S Mota,Fumio H Ito,Takeo Sakai,

To investigate the genetic characteristics of phosphoprotein (P) and matrix protein (M) genes of variable rabies virus (RV) prevalent in Brazil, the authors genetically characterized the P and M genes from 30 Brazilian RV field isolates. Phylogenetic analysis based on the P and M genes revealed the presence of six RV variants that consisted primarily of three insectivorous bats, the vampire bat, dog and fox in Brazil. Specific amino acid substitutions corresponding to these phylogenetic lineages were observed, with Asp(42) and Glu(62) in the P protein found to be characteristic of Brazilian chiroptera- and carnivora-related RVs, respectively. Amino acid sequence motifs predicted to associate with a viral function in the P and M proteins were conserved among Brazilian RV variants.

Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil. Publishing Authors By Initials

Y Kobayashi,H Okuda,K Nakamura,G Sato,T Itou,AA Carvalho,MV Silva,CS Mota,FH Ito,T Sakai,Y Kobayashi,H Okuda,K Nakamura,G Sato,T Itou,AA Carvalho,MV Silva,CS Mota,FH Ito,T Sakai,Y Kobayashi,H Okuda,K Nakamura,G Sato,T Itou,AA Carvalho,MV Silva,CS Mota,FH Ito,T Sakai,

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Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Journal of veterinary medical science / the Ja

VOLUME: 69

Page Numbers: 1145-54

Journal Abbreviation: J. Vet. Med. Sci.

ISSN: 0916-7250

DAY: 6

MONTH: Nov

YEAR: 2007

Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil. Information

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LANGUAGE: eng

NlmUniqueID: 9105360

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Grant and Affiliation Information for Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil.

AFFILIATION: Nihon University Veterinary Research Center, 1866 kameino, Fukisawa, Kanagawa 252-8510, Japan.

Country: Japan

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MEDLINETA: J Vet Med Sci

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