Generating short peptidic ligands for silver nanowires from phage display random libraries.

Generating short peptidic ligands for silver nanowires from phage display random libraries. Research Abstract Details 

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Generating short peptidic ligands for silver nanowires from phage display random libraries. Abstract Text:

Priscilla Chan,Tiffany Phan,Michael C Kao,Cheryl Dolan,Jeffrey B-H Tok,

We report the generation of peptide ligands for silver nanowires using a linear 12-mer peptide phage display random library technique. Phage clones that specifically bind the silver nanowires are sequenced after three rounds of biopanning, and obtained DNA sequences suggest that there are a few conserved amino acid residues which may be critical for binding. A selected binding peptide, together with two mutant peptide sequences, were subsequently synthesized on Tentagel resins to examine the importance of both the identities and positions of the conserved amino acid residues.

Generating short peptidic ligands for silver nanowires from phage display random libraries. Publishing Authors By Initials

P Chan,T Phan,MC Kao,C Dolan,JB Tok,

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Generating short peptidic ligands for silver nanowires from phage display random libraries. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Bioorganic & medicinal chemistry letters

VOLUME: 16

Page Numbers: 5261-4

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ISSN: 0960-894X

DAY: 24

MONTH: 08

YEAR: 2006

Generating short peptidic ligands for silver nanowires from phage display random libraries. Information

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LANGUAGE: eng

NlmUniqueID: 9107377

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Grant and Affiliation Information for Generating short peptidic ligands for silver nanowires from phage display random libraries.

AFFILIATION: Department of Chemistry and Materials Science, Biosecurity and Nanosciences Laboratory, Lawrence Livermore National Laboratory, University of California, Livermore, CA 94551, USA.

Country: England

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MEDLINETA: Bioorg Med Chem Lett

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