General health measures and long-term survival in patients with head and neck cancer.

General health measures and long-term survival in patients with head and neck cancer. Research Abstract Details 

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General health measures and long-term survival in patients with head and neck cancer. Abstract Text:

Laurent M Grignon,Mark J Jameson,Lucy Hynds Karnell,Alan J Christensen,Gerry F Funk,

OBJECTIVE: To determine whether a self-reported, subjective general health assessment tool can provide prognostic information about survival in patients with head and neck cancer. DESIGN: Prospective observational cohort study. SETTING: Tertiary care center. PATIENTS: Five hundred seventy-one patients with squamous cell carcinoma of the upper aerodigestive tract who were enrolled in the institution's longitudinal Outcomes Assessment Project between January 1, 1995, and November 30, 2004. MAIN OUTCOME MEASURES: Actuarial 5-year observed and disease-specific survival. RESULTS: The physical component summary obtained from the SF-36 (Medical Outcomes Study 36-Item Short-Form Health Survey) was significantly associated with ACE-27 (Adult Comorbidity Evaluation-27) comorbidity ratings. The mental component summary was not associated with ACE-27 scores or survival. Although the comorbidity rating was an independent predictor of observed survival (P = .002) only, the physical component summary was independently predictive of both observed (P<.001) and disease-specific (P = .001) survival. These associations continued to be independently significant when site and stage were included in the analysis (P = .003, P<.001, and P = .004, respectively). CONCLUSION: The physical component summary generated by the SF-36, a self-reported, subjective measure of general physical health, is predictive of both observed and disease-specific survival.

General health measures and long-term survival in patients with head and neck cancer. Publishing Authors By Initials

LM Grignon,MJ Jameson,LH Karnell,AJ Christensen,GF Funk,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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General health measures and long-term survival in patients with head and neck cancer. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Archives of otolaryngology--head & neck surgery

VOLUME: 133

Page Numbers: 471-6

Journal Abbreviation: Arch. Otolaryngol. Head Neck S

ISSN: 0886-4470

DAY: 3

MONTH: May

YEAR: 2007

General health measures and long-term survival in patients with head and neck cancer. Information

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LANGUAGE: eng

NlmUniqueID: 8603209

General health measures and long-term survival in patients with head and neck cancer. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: mortality

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Grant and Affiliation Information for General health measures and long-term survival in patients with head and neck cancer.

AFFILIATION: Department of Otolaryngology-Head and Neck Surgery, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242-1093, USA.

Country: United States

AGENCY: United States PHS

GRANT: R01-106908

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MEDLINETA: Arch Otolaryngol Head Neck Sur

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