Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain.

Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain. Research Abstract Details 

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Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain. Abstract Text:

Rui Lan Zhang,Zheng Gang Zhang,Michael Chopp,Rui Lan Zhang,Zheng Gang Zhang,Michael Chopp,

Focal cerebral ischemia induces neurogenesis in the subventricular zone (SVZ) of the adult human brain. Neurogenesis is controlled by proliferation, differentiation, and migration of neural progenitor cells. This article reviews emerging data that changes of cell cycle kinetics of neural progenitor cells induced by stroke contribute to increased neural progenitor cell proliferation and that gene profiles control proliferation, differentiation, and migration of neural progenitor cells within the SVZ niche. A better understanding of gene profiles that control the biological function of adult SVZ neural progenitor cells could lead to more selective and effective treatments to enhance neurogenesis during stroke recovery.

Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain. Publishing Authors By Initials

RL Zhang,ZG Zhang,M Chopp,RL Zhang,ZG Zhang,M Chopp,

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Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain. Journal Published:

PUBLICATION TYPE: Review

Journal: Current molecular medicine

VOLUME: 7

Page Numbers: 459-62

Journal Abbreviation: Curr. Mol. Med.

ISSN: 1566-5240

DAY: 13

MONTH: Aug

YEAR: 2007

Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain. Information

Number of References: 77

LANGUAGE: eng

NlmUniqueID: 101093076

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Grant and Affiliation Information for Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain.

AFFILIATION: Department of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.

Country: Netherlands

AGENCY: United States NINDS

GRANT: R01NS38292

ACRONYM: NS

MEDLINETA: Curr Mol Med

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