Gastrointestinal stromal tumours: Etiology, pathology and clinical management.

Gastrointestinal stromal tumours: Etiology, pathology and clinical management. Research Abstract Details 

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Gastrointestinal stromal tumours: Etiology, pathology and clinical management. Abstract Text:

Martin E Blackstein,Pierre ,Jonathan A Fletcher,Oliver R Keller,Margaret Knowling,Richard ,Donald Morris,Robert Riddell,Stewart Rorke,Carol J Swallow,

Investigation of the regulation of cell growth, differentiation and death by signalling pathways has led to a greater understanding of how alterations in these pathways play a critical role in the development of some cancers, and has opened new opportunities for their treatment. In the present review, results with the prototype drug of this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis, Switzerland), in metastatic gastrointestinal stromal tumours are presented. The present review originated from a conference of the authors held in Montreal, Quebec in June 2003, under the sponsorship of Novartis.

Gastrointestinal stromal tumours: Etiology, pathology and clinical management. Publishing Authors By Initials

ME Blackstein,P ,JA Fletcher,OR Keller,M Knowling,R ,D Morris,R Riddell,S Rorke,CJ Swallow,

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Gastrointestinal stromal tumours: Etiology, pathology and clinical management. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Canadian journal of gastroenterology = Journal can

VOLUME: 18 Suppl B

Page Numbers: 3B-8B

Journal Abbreviation: Can. J. Gastroenterol.

ISSN: 0835-7900

DAY: 30

MONTH: Sep

YEAR: 2004

Gastrointestinal stromal tumours: Etiology, pathology and clinical management. Information

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LANGUAGE: eng

NlmUniqueID: 8807867

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AFFILIATION: Mount Sinai Hospital, Toronto, Canada.

Country: Canada

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MEDLINETA: Can J Gastroenterol

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